• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

减少脊柱手术中植入物术前和术中污染的循证实践进展:一项叙述性综述

Updates on Evidence-Based Practices to Reduce Preoperative and Intraoperative Contamination of Implants in Spine Surgery: A Narrative Review.

作者信息

Agarwal Aakash, Lin Boren, Elgafy Hossein, Goel Vijay, Karas Chris, Schultz Christian, Anand Neel, Garfin Steve, Wang Jeffrey, Agarwal Anand

机构信息

Department of Biology, Bioengineering and Orthopaedics Surgery, University of Toledo, Toledo, USA.

Bone and Joint Center, OhioHealth Grant Medical, Columbus, USA.

出版信息

Spine Surg Relat Res. 2019 Jun 21;4(2):111-116. doi: 10.22603/ssrr.2019-0038. eCollection 2020.

DOI:10.22603/ssrr.2019-0038
PMID:32405555
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7217678/
Abstract

The current communication seeks to provide an updated narrative review on latest methods of reducing implant contaminations used during spine surgery. Recent literature review has shown that both preoperative reprocessing and intraoperative handling of implants seem to contaminate implants. In brief, during preoperative phase, the implants undergo repeated bulk cleaning with dirty instruments from the OR, leading to residue buildup at the interfaces and possibly on the surfaces too. This, due to its concealed nature, remains unnoticed by the SPD (sterile processing department) or other hospital staff. Nevertheless, these can be avoided by using individually prepackaged presterilized implants. In the intraoperative phase, the implants (in the sterile field) are directly touched by the scrub tech with soiled (assisting the surgeon dispose the tissues from the instruments in use) gloves for loading onto an insertion device. It is then kept exposed on the working table (either separately or next to the used instruments as the pedicles hole are being prepared). Latest investigation has shown that by the time it is implanted in the patient, it can harbor up to 10e7 bacterial colony-forming units. The same implants were devoid of such colony-forming units, when sheathed by an impermeable sterile sheath around the sterile implant.

摘要

本通讯旨在提供一篇最新的叙述性综述,介绍脊柱手术中减少植入物污染的最新方法。最近的文献综述表明,植入物的术前再处理和术中操作似乎都会导致植入物受到污染。简而言之,在术前阶段,植入物会与手术室的脏器械一起进行反复的批量清洁,导致界面处甚至表面也会有残留物堆积。由于其隐蔽性,消毒供应部门(SPD)或其他医院工作人员并未注意到这一点。然而,使用单独预包装的预灭菌植入物可以避免这些问题。在术中阶段,无菌区域内的植入物会被刷手技术员戴着脏手套(协助外科医生处理使用中的器械上的组织)直接触摸,以便装载到插入装置上。然后将其暴露在工作台上(单独放置或在准备椎弓根孔时放在用过的器械旁边)。最新研究表明,在植入患者体内时,它可能携带多达10的7次方个细菌菌落形成单位。当在无菌植入物周围包裹一层不透水的无菌护套时,同样的植入物则没有此类菌落形成单位。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/16829999e93f/2432-261X-4-0111-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/62d5dfbb178c/2432-261X-4-0111-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/53b987eafa5c/2432-261X-4-0111-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/f8db8399b8fb/2432-261X-4-0111-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/af930dcda292/2432-261X-4-0111-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/16829999e93f/2432-261X-4-0111-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/62d5dfbb178c/2432-261X-4-0111-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/53b987eafa5c/2432-261X-4-0111-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/f8db8399b8fb/2432-261X-4-0111-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/af930dcda292/2432-261X-4-0111-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ba62/7217678/16829999e93f/2432-261X-4-0111-g005.jpg

相似文献

1
Updates on Evidence-Based Practices to Reduce Preoperative and Intraoperative Contamination of Implants in Spine Surgery: A Narrative Review.减少脊柱手术中植入物术前和术中污染的循证实践进展:一项叙述性综述
Spine Surg Relat Res. 2019 Jun 21;4(2):111-116. doi: 10.22603/ssrr.2019-0038. eCollection 2020.
2
Efficacy of Intraoperative Implant Prophylaxis in Reducing Intraoperative Microbial Contamination.术中植入物预防措施在减少术中微生物污染方面的疗效
Global Spine J. 2019 Feb;9(1):62-66. doi: 10.1177/2192568218780676. Epub 2018 Jun 12.
3
Implant Prophylaxis: The Next Best Practice Toward Asepsis in Spine Surgery.植入物预防:脊柱手术无菌操作的下一个最佳实践
Global Spine J. 2018 Oct;8(7):761-765. doi: 10.1177/2192568218762380. Epub 2018 Apr 24.
4
A Multicenter Trial Demonstrating Presence or Absence of Bacterial Contamination at the Screw-Bone Interface Owing to Absence or Presence of Pedicle Screw Guard, Respectively, During Spinal Fusion.一项多中心试验,分别在脊柱融合过程中观察有无椎弓根螺钉保护套时螺钉骨界面的细菌污染情况。
Clin Spine Surg. 2020 Oct;33(8):E364-E368. doi: 10.1097/BSD.0000000000000976.
5
Implant contamination as a cause of surgical site infection in spinal surgery: are single-use implants a reasonable solution? - a systematic review.植入物污染作为脊柱手术手术部位感染的一个原因:一次性使用植入物是一个合理的解决方案吗?——一项系统评价
BMC Musculoskelet Disord. 2020 Sep 25;21(1):634. doi: 10.1186/s12891-020-03653-z.
6
Reprocessing safety issues associated with complex-design orthopaedic loaned surgical instruments and implants.与复杂设计的骨科租借手术器械和植入物相关的再处理安全问题。
Injury. 2018 Nov;49(11):2005-2012. doi: 10.1016/j.injury.2018.09.006. Epub 2018 Sep 5.
7
Harboring Contaminants in Repeatedly Reprocessed Pedicle Screws.反复再处理的椎弓根螺钉中存在污染物
Global Spine J. 2019 Apr;9(2):173-178. doi: 10.1177/2192568218784298. Epub 2018 Jun 25.
8
Implant contamination during spine surgery.脊柱手术中的植入物污染。
Spine J. 2013 Jun;13(6):637-40. doi: 10.1016/j.spinee.2012.11.053. Epub 2013 Jan 12.
9
Natural bioburden levels detected on rigid lumened medical devices before and after cleaning.清洁前后在刚性内腔医疗器械上检测到的自然生物负载水平。
Am J Infect Control. 1997 Dec;25(6):471-6. doi: 10.1016/s0196-6553(97)90070-5.
10
Surgical glove bacterial contamination and perforation during total hip arthroplasty implantation: when gloves should be changed.髋关节置换术中手术手套的细菌污染和穿孔:何时应更换手套。
Orthop Traumatol Surg Res. 2012 Jun;98(4):432-40. doi: 10.1016/j.otsr.2011.10.015. Epub 2012 May 10.

引用本文的文献

1
Synthesis and evaluation of a novel vancomycin-infused, biomimetic bone graft using a rat model of spinal implant-associated infection.使用脊柱植入物相关感染大鼠模型对新型万古霉素注入仿生骨移植材料的合成与评估
N Am Spine Soc J. 2024 Apr 9;18:100323. doi: 10.1016/j.xnsj.2024.100323. eCollection 2024 Jun.
2
A novel rodent model of chronic spinal implant-associated infection.一种新型慢性脊柱植入物相关感染的啮齿动物模型。
Spine J. 2023 Sep;23(9):1389-1399. doi: 10.1016/j.spinee.2023.05.014. Epub 2023 May 27.
3
High Prevalence of Biofilms on Retrieved Implants from Aseptic Pseudarthrosis Cases.

本文引用的文献

1
Harboring Contaminants in Repeatedly Reprocessed Pedicle Screws.反复再处理的椎弓根螺钉中存在污染物
Global Spine J. 2019 Apr;9(2):173-178. doi: 10.1177/2192568218784298. Epub 2018 Jun 25.
2
Efficacy of Intraoperative Implant Prophylaxis in Reducing Intraoperative Microbial Contamination.术中植入物预防措施在减少术中微生物污染方面的疗效
Global Spine J. 2019 Feb;9(1):62-66. doi: 10.1177/2192568218780676. Epub 2018 Jun 12.
3
Implant Prophylaxis: The Next Best Practice Toward Asepsis in Spine Surgery.植入物预防:脊柱手术无菌操作的下一个最佳实践
无菌性假关节病例取出的植入物上生物膜的高发生率。
Spine Surg Relat Res. 2020 Sep 23;5(2):104-108. doi: 10.22603/ssrr.2020-0147. eCollection 2021.
4
Future directions of postoperative spinal implant infections.术后脊柱植入物感染的未来发展方向。
J Spine Surg. 2020 Dec;6(4):814-819. doi: 10.21037/jss-20-585.
5
Implant Retention or Removal for Management of Surgical Site Infection After Spinal Surgery.脊柱手术后手术部位感染管理中植入物的保留或取出
Global Spine J. 2020 Aug;10(5):640-646. doi: 10.1177/2192568219869330. Epub 2019 Aug 11.
6
Progress not panacea: vancomycin powder efficacy and dose evaluated in an in vivo mouse model of spine implant infection.进展而非万灵药:万古霉素粉末在体内小鼠脊柱植入物感染模型中的疗效和剂量评估。
Spine J. 2020 Jun;20(6):973-980. doi: 10.1016/j.spinee.2019.12.007. Epub 2019 Dec 19.
Global Spine J. 2018 Oct;8(7):761-765. doi: 10.1177/2192568218762380. Epub 2018 Apr 24.
4
Revision spine surgery in patients without clinical signs of infection: How often are there occult infections in removed hardware?翻修无临床感染迹象的脊柱手术患者:取出的内固定物中有多少是隐匿性感染?
Eur Spine J. 2018 Oct;27(10):2491-2495. doi: 10.1007/s00586-018-5654-5. Epub 2018 Jun 20.
5
A Paradigm Shift Toward Terminally Sterilized Devices.向终端灭菌设备的范式转变。
Clin Spine Surg. 2018 Aug;31(7):308-311. doi: 10.1097/BSD.0000000000000675.
6
Pedicle screw loosening is correlated to chronic subclinical deep implant infection: a retrospective database analysis.椎弓根螺钉松动与慢性亚临床深部种植体感染相关:回顾性数据库分析。
Eur Spine J. 2018 Oct;27(10):2529-2535. doi: 10.1007/s00586-018-5592-2. Epub 2018 Apr 13.
7
Prevention of Surgical Site Infection in Spine Surgery.脊柱手术中手术部位感染的预防
Neurosurgery. 2017 Mar 1;80(3S):S114-S123. doi: 10.1093/neuros/nyw066.
8
Analysis of Postoperative Thoracolumbar Spine Infections in a Prospective Randomized Controlled Trial Using the Centers for Disease Control Surgical Site Infection Criteria.使用疾病控制中心手术部位感染标准的前瞻性随机对照试验中胸腰椎术后感染的分析
Int J Spine Surg. 2016 Apr 21;10:14. doi: 10.14444/3014. eCollection 2016.
9
Hospital uses team approach to improve processes, reduce costs.医院采用团队协作的方式来改进流程、降低成本。
AORN J. 1998 Jul;68(1):68-72. doi: 10.1016/s0001-2092(06)62715-4.