应对大流行期间新型病毒疫苗研发的挑战。
The Challenges of Vaccine Development against a New Virus during a Pandemic.
机构信息
Department of Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Molecular Microbiology, Washington University School of Medicine, St. Louis, MO 63110, USA; Department of Pathology & Immunology, Washington University School of Medicine, St. Louis, MO 63110, USA; Center for Human Immunology and Immunotherapy Programs, Washington University School of Medicine, St. Louis, MO 63110, USA.
Laboratory of Viral Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
出版信息
Cell Host Microbe. 2020 May 13;27(5):699-703. doi: 10.1016/j.chom.2020.04.021.
The rapid emergence of a highly pathogenic, readily transmissible coronavirus has resulted in a global pandemic, affecting millions and destabilizing economies. This catastrophe triggered a clarion call for the immediate deployment of a protective vaccine. We describe the unique challenges of developing a vaccine against SARS-CoV-2 in a pandemic setting.
一种高致病性、易传播的冠状病毒迅速出现，导致了一场全球性大流行，影响了数百万人，并使经济不稳定。这场灾难引发了立即部署保护性疫苗的紧急呼吁。我们描述了在大流行背景下开发针对 SARS-CoV-2 的疫苗所面临的独特挑战。
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