Department of Pharmacology, M. M. College of Pharmacy, M. M. (Deemeed to be University), Mullana, (Ambala), Haryana, India.
Department of Pharmacology, M. M. College of Pharmacy, M. M. (Deemeed to be University), Mullana, (Ambala), Haryana, India.
Pharmacol Res. 2020 Aug;158:104894. doi: 10.1016/j.phrs.2020.104894. Epub 2020 May 11.
Many flavonoids have various beneficial actions like anti-inflammatory, anti-carcinogenic properties and many other clinical conditions. Astilbin is one such flavanoid compound having many physiological as well as pharmacological actions.
To summarize the important findings from the research conducted using astilbin having significance to its physiological and pharmacological activities as well as the patents filed using astilbin.
Systematic review and compilation of the collected literature.
An extensive investigation of literature was done using several worldwide electronic scientific databases like PUBMED, SCOPUS, Science Direct and Google Scholar etc. All the article available in the English language that used our compound of interest i.e. astilbin, on the basis of inclusion criteria decided were retrieved from these databases, thoroughly reviewed and were summarized.
It has been established that astilbin can play a vital in the management of diseases associated with immune system. It also possesses antibacterial, anti-oxidative and hepatoprotective activity.
These researches provide evidence that astilbin possesses great potential and thus can be utilized in the management of various disorders, thus establishing itself as a potential candidate for novel drug development. Also, there is still room for research on astilbin like it can be evaluated for anticancer potential, protective effect in various diabetic complications and many more. Overall observations from data suggested that astilbin is a promising compound and proved its efficacy in every preclinical study which is conducted till date. Some of the pharmacological activity is still unexplored. After successful preclinical trials, astilbin can go for further clinical trials.
许多类黄酮具有多种有益作用，如抗炎、抗癌特性和许多其他临床病症。紫云英苷就是这样一种具有许多生理和药理作用的类黄酮化合物。
总结使用紫云英苷进行研究的重要发现，这些研究对其生理和药理活性以及使用紫云英苷申请的专利具有重要意义。
系统综述和文献汇编。
使用 PUBMED、SCOPUS、Science Direct 和 Google Scholar 等多个全球电子科学数据库，对文献进行了广泛的调查。从这些数据库中检索到所有基于纳入标准的、关于我们感兴趣的化合物即紫云英苷的可用英语文章，并进行了深入的综述和总结。
已经确定紫云英苷可以在管理与免疫系统相关的疾病方面发挥重要作用。它还具有抗菌、抗氧化和保肝活性。
这些研究为紫云英苷具有巨大潜力提供了证据，因此可以用于管理各种疾病，从而使其成为新药开发的潜在候选药物。此外，对紫云英苷的研究仍有空间，例如可以评估其抗癌潜力、在各种糖尿病并发症中的保护作用等。从数据中得出的总体观察结果表明，紫云英苷是一种很有前途的化合物，并证明了其在迄今为止进行的每一项临床前研究中的疗效。一些药理活性仍未得到探索。在成功的临床前试验之后，紫云英苷可以进行进一步的临床试验。
