Michael G. DeGroote Institute for Infectious Disease Research, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON L8S 4K1, Canada.
Michael G. DeGroote Institute for Infectious Disease Research, McMaster Immunology Research Centre, McMaster University, Hamilton, ON L8S 4K1, Canada; Department of Biochemistry and Biomedical Sciences, McMaster University, Hamilton, ON L8S 4K1, Canada.
Trends Microbiol. 2020 Sep;28(9):703-706. doi: 10.1016/j.tim.2020.04.006. Epub 2020 Apr 20.
MHC class II (MHCII) has recently been identified as a cellular receptor for bat influenza viruses. Here, we discuss the possible implications of viral exploitation of this critical host defense molecule and highlight the need for more intense study of bat-influenza virus interactions.
MHC 类 II(MHCII)最近被鉴定为蝙蝠流感病毒的细胞受体。在这里,我们讨论了病毒利用这种关键宿主防御分子的可能影响,并强调需要加强对蝙蝠-流感病毒相互作用的研究。