Department of Veterinary Pathobiology, College of Veterinary Medicine, University of Missouri, Columbia, MO 65211, USA.
Department of Molecular Microbiology and Immunology, School of Medicine, University of Missouri, Columbia, MO 65211, USA.
Viruses. 2021 Mar 25;13(4):547. doi: 10.3390/v13040547.
Bats are natural reservoirs for many viruses, including several that are zoonotic. Two unusual H17N10 and H18N11 influenza viruses have been found in New World bats. Although neither of these viruses have been isolated, infectious clone technology has permitted significant progress to understand their biology, which include unique features compared to all other known influenza A viruses. In addition, an H9N2-like influenza A virus was isolated from Old World bats and it shows similar characteristics of normal influenza A viruses. In this review, current status and perspective on influenza A viruses identified in bats is reviewed and discussed.
蝙蝠是许多病毒的天然宿主，包括几种人畜共患病毒。两种不寻常的 H17N10 和 H18N11 流感病毒已在新世界蝙蝠中被发现。尽管这些病毒都尚未被分离出来，但感染性克隆技术已经取得了显著进展，使人们对其生物学特性有了深入了解，与所有其他已知的甲型流感病毒相比，这些病毒具有独特的特征。此外，还从旧世界蝙蝠中分离出了一种类似 H9N2 的甲型流感病毒，它表现出与正常甲型流感病毒相似的特征。在本文中，对在蝙蝠中发现的甲型流感病毒的现状和前景进行了综述和讨论。
