Moribuchi Hayato, Sato Rumi, Matsushima Shuntaro, Tominaga Masaki, Sasaki Jun, Nakamura Masayuki, Sakazaki Yuki, Nishiyama Mamoru, Hoshino Tomoaki, Kawayama Tomotaka
Division of Respirology, Neurology, and Rheumatology, Department of Medicine, Kurume University School of Medicine, Japan.
Respiratory Medicine, Asakura Medical Association Hospital, Japan.
Intern Med. 2020;59(10):1295-1298. doi: 10.2169/internalmedicine.3857-19. Epub 2020 May 15.
A 56-year-old healthy man who was a current smoker died from fulminant tracheobronchial aspergillosis despite a month of treatment with a combination of intravenous anti-fungal agents that had been started immediately after the diagnosis. This case report is important for understanding and managing fulminant Aspergillus infections in healthy subjects, although the pathogenesis and underlying pathways are still unknown.
一名56岁的健康男性,目前仍在吸烟,尽管在诊断后立即开始联合使用静脉抗真菌药物进行了一个月的治疗,但仍死于暴发性气管支气管曲霉病。本病例报告对于了解和处理健康受试者中的暴发性曲霉感染很重要,尽管其发病机制和潜在途径仍不清楚。