Liu Xuebing, Lin Hong, Jiang Haifeng, Li Ruihua, Zhong Na, Su Hang, Li Yi, Zhao Min
Wuhan Mental Health Center, Wuhan, China.
Yichang Special Care Hospital, Yichang, China.
Gen Psychiatr. 2020 Apr 20;33(2):e100222. doi: 10.1136/gpsych-2020-100222. eCollection 2020.
Since the outbreak of COVID-19, no data have been available for hospitalised psychiatric patients who are suspected to have COVID-19. We performed a comprehensive investigation of the clinical features of hospitalised patients with schizophrenia with or without suspected COVID-19 in Hubei Province, China.
To explore the clinical characteristics of hospitalised patients with schizophrenia with suspected COVID-19 in Hubei Province, China.
21 hospitalised patients with schizophrenia with suspected COVID-19 (COVID-19 suspected group) in the isolation ward of a mental health hospital in Wuhan and 30 hospitalised patients with schizophrenia (clean group) in the general ward of another mental health hospital in Yichang were recruited. We retrospectively reviewed their clinical characteristics, laboratory findings and chest CT results before 21 February 2020. We also compared the emotional and mental symptoms between the two groups.
Medical records revealed that 21 COVID-19 suspected patients were transferred to the isolation ward between 30 January 2020 and 15 February 2020. The mean age (SD) of COVID-19 suspected patients was 43.1 (2.6). 12 (57.1%) patients showed abnormalities on chest CT before onset of respiratory symptoms. 14 (66.7%) patients had psychiatric medications adjustment after detection of abnormal chest CT findings. By 21 February, one patient was confirmed to have COVID-19. Even though the remaining 20 (95.2%) were negative for at least two reverse transcription PCR tests, 11 (52.4%) patients met the diagnostic criteria for clinically confirmed cases. Compared with patients in the clean group, patients in the suspected COVID-19 group showed significantly higher stress, depression and anxiety levels and poorer sleep quality.
Setting up an independent isolation ward for hospitalised psychiatric patients who are suspected to have symptoms of COVID-19 helped control the spread of the epidemic. Patients with schizophrenia suspected to have COVID-19 showed increased stress and mood and sleep disturbances, which should be appropriately managed.
自新型冠状病毒肺炎（COVID-19）疫情爆发以来，尚无关于疑似感染COVID-19的住院精神科患者的数据。我们对中国湖北省住院的合并或未合并疑似COVID-19的精神分裂症患者的临床特征进行了全面调查。
探讨中国湖北省住院的疑似COVID-19的精神分裂症患者的临床特征。
招募了武汉市一家精神卫生医院隔离病房的21例住院疑似COVID-19的精神分裂症患者（COVID-19疑似组）和宜昌市另一家精神卫生医院普通病房的30例住院精神分裂症患者（清洁组）。我们回顾性分析了他们在2020年2月21日前的临床特征、实验室检查结果和胸部CT结果。我们还比较了两组之间的情绪和精神症状。
病历显示，21例COVID-19疑似患者于2020年1月30日至2月15日期间被转移至隔离病房。COVID-19疑似患者的平均年龄（标准差）为43.1（2.6）岁。12例（57.1%）患者在出现呼吸道症状前胸部CT显示异常。14例（66.7%）患者在胸部CT检查发现异常后调整了精神科药物。截至2月21日，1例患者确诊为COVID-19。尽管其余20例（95.2%）至少两次逆转录聚合酶链反应检测为阴性，但11例（52.4%）患者符合临床确诊病例的诊断标准。与清洁组患者相比，COVID-19疑似组患者的压力、抑郁和焦虑水平显著更高，睡眠质量更差。
为疑似有COVID-19症状的住院精神科患者设立独立隔离病房有助于控制疫情传播。疑似感染COVID-19 的精神分裂症患者的压力、情绪和睡眠障碍增加，应予以适当处理。
