Santos Fernando Azenha Bautzer, Lemes Renan Barbosa, Otto Paulo Alberto
Universidade de São Paulo, Instituto de Biociências, Departamento de Genética e Biologia Evolutiva, Laboratório de Genética Humana, São Paulo, SP, Brazil.
Genet Mol Biol. 2020 May 11;43(2):e20190380. doi: 10.1590/1678-4685-GMB-2019-0380.
This article deals with a Windows (© Microsoft Inc.) executable, user-friendly program that tests the hypothesis of Hardy-Weinberg (HW) proportions from autosomal multiallelic data using different methods that include parametric, nonparametric and exact bootstrap tests, the latter obtained through computer simulations. The program can be obtained free of charge directly from the internet repository https://github.com/Lemes-RenanB/HardyWeinbergTesting.
本文介绍了一个适用于Windows（©微软公司）的可执行、用户友好型程序，该程序使用不同方法（包括参数检验、非参数检验和精确自举检验，精确自举检验通过计算机模拟获得）来检验常染色体多等位基因数据的哈迪-温伯格（HW）比例假设。该程序可直接从互联网资源库https://github.com/Lemes-RenanB/HardyWeinbergTesting免费获取。
