非结核分枝杆菌的鉴定和药敏试验。
Identification and drug susceptibility testing for nontuberculous mycobacteria.
机构信息
Division of Chest Medicine, Department of Internal Medicine, Taichung Veterans General Hospital, Taichung, 407, Taiwan; Department of Medical Technology, Jen-Teh Junior College of Medicine, Nursing and Management, Miaoli, 350, Taiwan; Department of Life Sciences, National Chung-Hsing University, Taichung, 402, Taiwan; Department of Industrial Engineering and Enterprise Information, Tunghai University, Taichung, 407, Taiwan.
Division of Pulmonary Medicine, Department of Internal Medicine, Wan Fang Hospital, Taipei, 116, Taiwan; School of Respiratory Therapy, College of Medicine, Taipei Medical University, Taipei, 110, Taiwan.
出版信息
J Formos Med Assoc. 2020 Jun;119 Suppl 1:S32-S41. doi: 10.1016/j.jfma.2020.05.002. Epub 2020 May 16.
Great progress has recently been made in methodologies for identifying nontuberculous mycobacteria (NTM). Recommendations for drug susceptibility testing (DST) of NTM have been expanded and updated by the Clinical and Laboratory Standards Institute and are crucial in the management of NTM infections. This article summarizes the clinically relevant molecular methods used to discriminate NTM species and updates the information on DST. Furthermore, recent progress on new antimicrobials against NTM infections is reviewed.
近年来，在鉴定非结核分枝杆菌（NTM）的方法学方面取得了重大进展。临床和实验室标准协会扩大并更新了非结核分枝杆菌药物敏感性测试（DST）的建议，这对非结核分枝杆菌感染的管理至关重要。本文总结了用于区分非结核分枝杆菌物种的临床相关分子方法，并更新了关于 DST 的信息。此外，还综述了针对非结核分枝杆菌感染的新抗菌药物的最新进展。
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