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类风湿关节炎患者的足部健康和生活质量:一项横断面研究。

Foot health and quality of life in patients with rheumatoid arthritis: a cross-sectional study.

机构信息

Departamento de Reumatologia, Hospital Universitario Virgen de las Nieves, Granada, Spain.

Department Nursing and Podiatry, Universidad de Málaga, Instituto de Investigación Biomédica de Málaga (IBIMA), Malaga, Spain

出版信息

BMJ Open. 2020 May 17;10(5):e036903. doi: 10.1136/bmjopen-2020-036903.

Abstract

OBJECTIVE

The aim of this study is to identify foot health factors related to the quality of life in patients with rheumatoid arthritis (RA).

SETTING

In this cross-sectional study, a total of 293 subjects were analysed, 229 of whom were in the RA group and 64 in the control group. In the RA group, 173 patients were female, and 50 in the control group.

PARTICIPANTS

Patients with foot pain and RA (according to the American College of Rheumatology/European League Against Rheumatism 2010 rheumatoid arthritis classification criteria) and with foot pain but no RA were recruited (Granada, Spain).

INTERVENTION

Two researchers independently interviewed the patients to obtain data for the study.

PRIMARY AND SECONDARY OUTCOME MEASURES

Clinical data were obtained using the Short Form 12-Item questionnaire (quality of life) (primary outcome), Visual Analogue Scale for pain (VAS pain), the Manchester Foot Pain Disability Index (MFPDI) and the Foot Function Index (FFI). Anthropometric measurements were obtained using a foot measurement platform, the Foot Posture Index and the Manchester Scale of Hallux Valgus (secondary outcomes).

RESULTS

Of the 293 subjects, 76.1% were female. Significant differences were observed between the RA and the control group (p<0.001) with regard to VAS pain (general, foot and hand), MFPDI and FFI. In terms of anthropometric measurements, significant differences were only recorded for midfoot and forefoot width (p=0.03). For the physical health component, multivariable linear regression with the parameters age, gender, VAS pain (general) and the presence of RA presented an R value of 48.8%, while for the mental health component the corresponding value was 5.6%.

CONCLUSION

Morphological and structural characteristics of the foot are not necessarily associated with pain, disability and loss of function. The presence of RA, a higher score on VAS pain (general), female gender and older age are all associated with the physical component of the quality of life of patients with RA.

摘要

目的

本研究旨在确定与类风湿关节炎(RA)患者生活质量相关的足部健康因素。

设置

在这项横断面研究中,共分析了 293 名受试者,其中 229 名为 RA 组,64 名为对照组。在 RA 组中,173 名患者为女性,对照组中 50 名。

参与者

招募了足部疼痛且患有 RA(根据美国风湿病学会/欧洲抗风湿病联盟 2010 年 RA 分类标准)以及足部疼痛但未患 RA 的患者(西班牙格拉纳达)。

干预

两名研究人员独立对患者进行访谈以获取研究数据。

主要和次要结果测量

使用简短 12 项健康调查量表(生活质量)(主要结果)、视觉模拟量表疼痛(VAS 疼痛)、曼彻斯特足部疼痛残疾指数(MFPDI)和足部功能指数(FFI)获得临床数据。使用足部测量平台、足弓指数和曼彻斯特拇外翻量表(次要结果)获得人体测量数据。

结果

在 293 名受试者中,76.1%为女性。RA 组与对照组之间在 VAS 疼痛(全身、足部和手部)、MFPDI 和 FFI 方面存在显著差异(p<0.001)。在人体测量方面,仅中足和前足宽度记录到显著差异(p=0.03)。对于身体健康成分,多变量线性回归分析参数为年龄、性别、VAS 疼痛(全身)和 RA 的存在,其 R 值为 48.8%,而心理健康成分的相应值为 5.6%。

结论

足部的形态和结构特征不一定与疼痛、残疾和功能丧失相关。RA 的存在、VAS 疼痛(全身)评分较高、女性和年龄较大与 RA 患者生活质量的身体成分相关。

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