Center for Dermatology Research, Department of Dermatology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, NC, 27157-1071, USA.
Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
Am J Clin Dermatol. 2020 Aug;21(4):505-511. doi: 10.1007/s40257-020-00521-3.
Psoriasis is a chronic immune-mediated inflammatory disease that predominantly affects the skin and joints. Its detrimental effects on the physical, psychosocial, and emotional well-being of patients leads to a significant reduction in quality of life (QoL). The goals of treatment focus on decreasing disease severity and improving QoL for patients; accomplishing these goals requires physicians to understand both the full impact of the disease on a patient's life and the outcomes that matter most to patients. The use of outcome measures, both physician- and patient-reported, can assist clinicians in evaluating the disease burden and its effect on QoL and in identifying patient preferences for treatment, ultimately enhancing quality of care. However, current outcome measures have many limitations and do not adequately capture patients' needs and priorities. Nevertheless, physicians treating patients with psoriasis are encouraged to utilize these instruments while remaining cognizant of each of their limitations. As there is no consensus on an outcome measure that fully encompasses the complexities of psoriasis and its impact on patients, instruments that are appropriate and applicable to dermatologists and their patients should be developed.
银屑病是一种慢性免疫介导的炎症性疾病，主要影响皮肤和关节。它对患者身体、心理社会和情感健康的不良影响导致生活质量（QoL）显著下降。治疗的目标是降低疾病的严重程度并改善患者的 QoL；实现这些目标需要医生既了解疾病对患者生活的全面影响，又了解对患者最重要的结果。使用医生和患者报告的结果衡量标准可以帮助临床医生评估疾病负担及其对 QoL 的影响，并确定患者对治疗的偏好，从而最终提高护理质量。然而，目前的结果衡量标准存在许多局限性，不能充分满足患者的需求和重点。尽管如此，仍鼓励治疗银屑病患者的医生使用这些工具，同时注意到它们各自的局限性。由于没有一种结果衡量标准能够完全涵盖银屑病的复杂性及其对患者的影响，因此应开发适合皮肤科医生及其患者的合适和适用的工具。
