Department of Veterinary Sciences, University of Pisa, Pisa, Italy.
Department of Clinical Science and Translational Medicine, University of Rome "Tor Vergata", Rome, Italy.
Open Vet J. 2020 Apr;10(1):74-79. doi: 10.4314/ovj.v10i1.12. Epub 2020 Mar 18.
Canine primary chronic enteropathy (CE) includes a heterogeneous group of diseases characterized by chronic gastrointestinal signs.
This study evaluated the occurrence of infection in primary CE-affected dogs.
Forty-seven CE-affected dogs of different age and sex were enrolled in the study. For each dog, frequency of defecation, fecal consistency, and eventual fecal abnormalities were evaluated. A clinical scoring index of CE severity (clinical chronic enteropathy activity index) was also assessed, and the type of enteropathy was retrospectively classified. For parasitological analysis, fresh fecal samples collected from each dog were examined by fresh and Lugol stained smears, flotation test, and a rapid immunoassay. genotypes were identified by molecular analysis. Differences of clinical parameters between positive and negative dogs were statistically evaluated.
Among the CE canine patients, 16 out of 47 (34%) dogs were found positive for and assemblages C and D were identified. No statistical differences emerged according to the types of CE between -positive and -negative dog groups. The clinical index of CE severity was indicative of significant less severe clinical forms in -positive dogs ( = 0.037).
Results here obtained shows how may be present in primary CE-affected dogs and further investigations are needed to clarify the real significance of mild clinical presentation in -positive dogs affected by CE.
犬原发性慢性肠炎(CE)包括一组以慢性胃肠道症状为特征的异质性疾病。
本研究评估了原发性 CE 犬感染的发生情况。
本研究纳入了 47 只不同年龄和性别的 CE 犬。对每只狗的排便频率、粪便稠度和粪便异常情况进行评估。还评估了 CE 严重程度的临床评分指数(临床慢性肠炎活动指数),并回顾性分类肠炎类型。为了进行寄生虫分析,从每只狗采集新鲜粪便样本,通过新鲜和卢戈氏染色涂片、漂浮试验和快速免疫测定进行检查。通过分子分析确定 基因型。统计评估了 阳性和 阴性犬之间临床参数的差异。
在 CE 犬患者中,47 只犬中有 16 只(34%)犬 阳性,鉴定出了 C 和 D 型。在 CE 阳性和阴性犬组之间,没有观察到不同类型的 CE 之间存在统计学差异。CE 严重程度的临床指数表明,阳性犬的临床症状明显较轻(=0.037)。
本研究结果表明, 可能存在于原发性 CE 犬中,需要进一步研究来阐明在患有 CE 的 阳性犬中轻度临床症状的真正意义。