过去十年中，用于取代苯并呋喃合成的非常规方法。
Last Decade of Unconventional Methodologies for the Synthesis of Substituted Benzofurans.
机构信息
Department of Science, Via dell'Ateneo Lucano, 10, 85100 Potenza, Italy.
出版信息
Molecules. 2020 May 16;25(10):2327. doi: 10.3390/molecules25102327.
This review describes the progress of the last decade on the synthesis of substituted benzofurans, which are useful scaffolds for the synthesis of numerous natural products and pharmaceuticals. In particular, new intramolecular and intermolecular C-C and/or C-O bond-forming processes, with transition-metal catalysis or metal-free are summarized. (1) Introduction. (2) Ring generation via intramolecular cyclization. (2.1) C7a-O bond formation: (route a). (2.2) O-C2 bond formation: (route b). (2.3) C2-C3 bond formation: (route c). (2.4) C3-C3a bond formation: (route d). (3) Ring generation via intermolecular cyclization. (3.1) C7a-O and C3-C3a bond formation (route a + d). (3.2) O-C2 and C2-C3 bond formation: (route b + c). (3.3) O-C2 and C3-C3a bond formation: (route b + d). (4) Benzannulation. (5) Conclusion.
这篇综述描述了过去十年中取代苯并呋喃合成方面的进展，苯并呋喃是合成许多天然产物和药物的有用骨架。特别地，总结了新的、涉及分子内和分子间 C-C 和/或 C-O 键形成过程的方法，这些方法涉及过渡金属催化或无金属催化。(1) 引言。(2) 通过分子内环化生成环。(2.1) C7a-O 键形成：(路线 a)。(2.2) O-C2 键形成：(路线 b)。(2.3) C2-C3 键形成：(路线 c)。(2.4) C3-C3a 键形成：(路线 d)。(3) 通过分子间环化生成环。(3.1) C7a-O 和 C3-C3a 键形成(路线 a + d)。(3.2) O-C2 和 C2-C3 键形成：(路线 b + c)。(3.3) O-C2 和 C3-C3a 键形成：(路线 b + d)。(4) 苯并环化。(5) 结论。
Zotero 插件