Department of Cardiology, Faculty of Medicine, Cardiovascular Research Center, Mazandaran University of Medical Sciences, Sari, Iran.
Department of Pharmaceutics, School of Pharmacy, Mazandaran University of Medical Sciences, Sari, Iran.
BMC Cardiovasc Disord. 2020 May 19;20(1):238. doi: 10.1186/s12872-020-01526-w.
Prevalence of coronary heart disease (CHD) risk factors are increasing in developing countries. The present study aimed to assess the prevalence of self-reported CHD and evaluate the role of various risk factors on its prevalence in the Tabari cohort study (TCS) population.
The enrollment phase of TCS was performed between June 2015 and November 2017. In the current study, data were derived from information collecting from the enrollment phase of TCS. In the enrollment phase, 10,255 individuals aged 35-70 living in urban and mountainous areas of Sari (northern part of Iran) were entered into the study. Educational level, socioeconomic and marital status, history of smoking, opium and alcohol abuse/addiction, level of daily physical activity, indices of obesity, and traditional risk factors of the participants were determined.
The prevalence of CHD was measured at 9.2%. Older individuals (P<0.001), people with a body mass index≥30kg/m2 (P<0.001), diabetics (P<0.001), and hypertensive (P<0.001) have been shown to have an increased risk for CHD compared with participants of without CHD. Furthermore, the CHD was more prevalent in individuals with higher waist circumference (P<0.001), higher low-density lipoprotein cholesterol (P<0.001), lower high-density lipoprotein cholesterol (P<0.001), and a higher waist to hip ratio (P<0.001). In addition, individuals with low socioeconomic status, illiterate people, and opium users had a higher prevalence of CHD (P<0.001). The results of the multivariable logistic regression analysis showed that the probability of CHD among individuals who had 8-10 risk factors was estimated at 8.41 (95% confidence interval: 5.75-12.31) times higher than those with less than 3 risk factors.
According to the results of the present study, it seems that the prevalence of CHD in the Iranian population is relatively high.
冠心病（CHD）危险因素在发展中国家的流行率正在上升。本研究旨在评估报告的 CHD 的流行率，并评估各种危险因素对塔巴里队列研究（TCS）人群中 CHD 流行率的作用。
TCS 的招募阶段于 2015 年 6 月至 2017 年 11 月进行。在本研究中，数据来自 TCS 招募阶段的信息收集。在招募阶段，有 10255 名年龄在 35-70 岁的人居住在伊朗北部的萨里（Sari）的城市和山区，进入了这项研究。确定了参与者的教育程度、社会经济和婚姻状况、吸烟、滥用鸦片和酒精的历史、日常身体活动水平、肥胖指数以及传统的危险因素。
CHD 的患病率为 9.2%。与无 CHD 的参与者相比，年龄较大的个体（P<0.001）、身体质量指数≥30kg/m2 的个体（P<0.001）、糖尿病患者（P<0.001）和高血压患者（P<0.001）患 CHD 的风险增加。此外，腰围较大（P<0.001）、低密度脂蛋白胆固醇较高（P<0.001）、高密度脂蛋白胆固醇较低（P<0.001）和腰臀比较高（P<0.001）的个体 CHD 更为普遍。此外，社会经济地位较低、文盲和鸦片使用者的 CHD 患病率较高（P<0.001）。多变量逻辑回归分析的结果表明，与风险因素少于 3 个的个体相比，具有 8-10 个风险因素的个体患 CHD 的概率估计为 8.41 倍（95%置信区间：5.75-12.31）。
根据本研究的结果，伊朗人群中 CHD 的流行率似乎相对较高。
