塔巴里队列人群贫血的患病率及相关因素：一项横断面研究。

Prevalence of anemia and related factors among Tabari cohort population: a cross-sectional study.

机构信息

Student Research Committee, School of Medicine, Mazandaran University of Medical Sciences, Sari, Iran.

Health Sciences Research Center, Mazandaran University of Medical Sciences, Sari, Iran.

出版信息

BMC Public Health. 2024 Oct 3;24(1):2702. doi: 10.1186/s12889-024-20220-6.

DOI:10.1186/s12889-024-20220-6

PMID:39363176

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11450993/

Abstract

BACKGROUND

Anemia presents a considerable public health challenge, standing as a leading contributor to elevated rates of mortality and morbidity. Therefore, this study aimed to investigate the prevalence of anemia and related factors among Tabari cohort population.

METHODS

This study involved a cross-sectional investigation carried out during the enrollment phase of the Tabari cohort. The Tabari cohort is a subset of the larger nationwide cohort study known as the "Prospective Epidemiological Research Studies in IrAN" (PERSIAN) cohort. The collected data included general information, anthropometric measurements, medical history and blood samples. Anemia was defined as a hemoglobin level less than 13 mg/dL for men and less than 12 mg/dL for women. Data were analyzed using SPSS V.16.

RESULTS

Out of the 10,073 participants included in the analysis, 1,352 individuals (13.4%) were diagnosed with anemia. In the multiple regression analysis, the odds of anemia were significantly 2.31 times in females compared to males, 3.69 times in urban residents compared to rural residents, 1.41 times in social economic categories of IV and 1.35 in social economic categories of V compared to social economic categories of I, 1.70 times in drug abuse compared to non-drug abuse, 0.71 times in body mass index (BMI) categories of 25-29.9 kg/m² and 0.70 in BMI ≥ 30 kg/m² compared to BMI < 25, 0.77 times for triglycerides(TG) > 150 compared to below 150, 0.76 times for total cholesterol(TC) > 200 compared to below 200, 0.83 times for high waist-to-hip ratio (WHR) compared to low WHR, 1.33 times in low High-density Lipoprotein (HDL) compared to high HDL, 1.18 times in diabetics (DM) compared to non-DM, and 1.37 times in individuals with coronary heart diseases (CHD) compared to healthy individuals.

CONCLUSION

Anemia was a prevalent condition among Tabari cohort population. Several conditions including female gender, urban residence, Social economic level of IV and V, drug abuse, low HDL, high WHR, DM, and CHD conditions were significantly associated with increased odds of anemia. Furthermore, BMI categories of 25-29.9 kg/m² and ≥ 30 kg/m², high TC and high TG were significantly associated with decreased odds of anemia among this population.

摘要

背景

贫血对公共健康构成了重大挑战，是导致死亡率和发病率升高的主要因素之一。因此，本研究旨在调查塔里布队列人群中贫血的患病率及其相关因素。

方法

本研究为塔里布队列的横断面研究。塔里布队列是全国范围的前瞻性流行病学研究在伊朗（PERSIAN）队列研究的一个子集。收集的数据包括一般信息、人体测量学指标、病史和血液样本。贫血定义为男性血红蛋白水平<13mg/dL，女性血红蛋白水平<12mg/dL。采用 SPSS V.16 进行数据分析。

结果

在纳入分析的 10073 名参与者中，有 1352 人（13.4%）被诊断为贫血。在多因素回归分析中，女性贫血的风险比男性高 2.31 倍，城市居民贫血的风险比农村居民高 3.69 倍，社会经济类别 IV 和 V 贫血的风险比社会经济类别 I 高 1.41 倍，药物滥用者贫血的风险比非药物滥用者高 1.70 倍，体质指数（BMI）类别 25-29.9kg/m²的贫血风险比 BMI<25 的低 0.71 倍，BMI≥30kg/m²的贫血风险比 BMI<25 的低 0.70 倍，甘油三酯（TG）>150 的贫血风险比 TG<150 的高 0.77 倍，总胆固醇（TC）>200 的贫血风险比 TC<200 的高 0.76 倍，腰臀比（WHR）高的贫血风险比 WHR 低的高 0.83 倍，高密度脂蛋白（HDL）低的贫血风险比 HDL 高的高 1.33 倍，糖尿病（DM）患者贫血的风险比非 DM 患者高 1.18 倍，冠心病（CHD）患者贫血的风险比健康人群高 1.37 倍。