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在新冠大流行期间,卒中 CT 血管造影上偶然发现与 COVID-19 相关的肺尖病变。

Incidental COVID-19 related lung apical findings on stroke CTA during the COVID-19 pandemic.

机构信息

Diagnostic, Molecular and Interventional Radiology, Mount Sinai Health System, New York, New York, USA

Diagnostic, Molecular and Interventional Radiology, Mount Sinai Health System, New York, New York, USA.

出版信息

J Neurointerv Surg. 2020 Jul;12(7):669-672. doi: 10.1136/neurintsurg-2020-016188. Epub 2020 May 19.

DOI:10.1136/neurintsurg-2020-016188
PMID:32430481
Abstract

BACKGROUND

Authors have noticed an increase in lung apex abnormalities on CT angiography (CTA) of the head and neck performed for stroke workup during the coronavirus disease 2019 (COVID-19) pandemic.

OBJECTIVE

To evaluate the incidence of these CTA findings and their relation to COVID-19 infection.

METHODS

In this retrospective multicenter institutional review board-approved study, assessment was made of CTA findings of code patients who had a stroke between March 16 and April 5, 2020 at six hospitals across New York City. Demographic data, comorbidities, COVID-19 status, and neurological findings were collected. Assessment of COVID-19 related lung findings on CTA was made blinded to COVID-19 status. Incidence rates of COVID-19 related apical findings were assessed in all code patients who had a stroke and in patients with a stroke confirmed by imaging.

RESULTS

The cohort consisted of a total of 118 patients with mean±SD age of 64.9±15.7 years and 57.6% (68/118) were male. Among all code patients who had a stroke, 28% (33/118) had COVID-19 related lung findings. RT-PCR was positive for COVID-19 in 93.9% (31/33) of these patients with apical CTA findings.Among patients who had a stroke confirmed by imaging, 37.5% (18/48) had COVID-19 related apical findings. RT-PCR was positive for COVID-19 in all (18/18) of these patients with apical findings.

CONCLUSION

The incidence of COVID-19 related lung findings in stroke CTA scans was 28% in all code patients who had a stroke and 37.5% in patients with a stroke confirmed by imaging. Stroke teams should closely assess the lung apices during this COVID-19 pandemic as CTA findings may be the first indicator of COVID-19 infection.

摘要

背景

作者注意到,在 2019 年冠状病毒病(COVID-19)大流行期间,为中风检查而进行的头颈部 CT 血管造影(CTA)中,肺尖异常的情况有所增加。

目的

评估这些 CTA 结果的发生率及其与 COVID-19 感染的关系。

方法

在这项回顾性多中心机构审查委员会批准的研究中,对 2020 年 3 月 16 日至 4 月 5 日期间在纽约市六家医院就诊的中风代码患者的 CTA 结果进行了评估。收集了人口统计学数据、合并症、COVID-19 状态和神经学发现。对 CTA 上 COVID-19 相关肺部发现的评估是在对 COVID-19 状态进行盲法的情况下进行的。在所有中风代码患者中以及在经影像学证实有中风的患者中,评估 COVID-19 相关尖部发现的发生率。

结果

该队列共包括 118 名患者,平均年龄为 64.9±15.7 岁,57.6%(68/118)为男性。在所有有中风的代码患者中,28%(33/118)有 COVID-19 相关肺部发现。这些有 CTA 尖部发现的患者中,93.9%(31/33)的 RT-PCR 检测 COVID-19 阳性。在经影像学证实有中风的患者中,37.5%(18/48)有 COVID-19 相关尖部发现。所有这些有尖部发现的患者(18/18)的 RT-PCR 检测 COVID-19 均为阳性。

结论

在所有有中风的代码患者中,COVID-19 相关肺部发现的发生率为 28%,在经影像学证实有中风的患者中为 37.5%。在 COVID-19 大流行期间,中风团队应密切评估肺部尖部,因为 CTA 结果可能是 COVID-19 感染的第一个指标。

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