RE Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, the National Academy of Sciences of Ukraine, Kyiv, Ukraine.
Institute for Nuclear Research, the National Academy of Sciences of Ukraine, Kyiv, Ukraine.
Ann Hematol. 2020 Jul;99(7):1543-1550. doi: 10.1007/s00277-020-04076-5. Epub 2020 May 19.
The major sources of the data on the hematological malignancies in the post-Chernobyl period in the regions of Ukraine differing by the levels of the residual contamination with radionuclides have been analyzed. According to the data collected from the primary hematological facilities in Ukraine in 2010-2017, the incidence of lymphoid neoplasms from mature B cells, acute myeloid leukemia, and multiple myeloma in the most contaminated regions was higher than in the less contaminated ones. For the first time, the relative contribution of the several specific types of leukemia in the total diagnosed hematological malignancies has been analyzed throughout 1997-2017 based on the in-house database compiled by the Reference Laboratory of RE Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology, the National Academy of Sciences of Ukraine. In 2011-2017, the Reference Laboratory provided the diagnostic studies in about 26% of all Ukrainian patients with tumors of hematopoietic and lymphoid tissues (34% of patients with different forms of acute and chronic leukemia). The increased proportion of acute myeloid leukemia and chronic lymphocytic leukemia in the total diagnosed cases of overall leukemia in the patients from contaminated regions has been demonstrated following Chernobyl accident.
分析了乌克兰不同放射性核素残留污染水平地区后切尔诺贝利时期血液病数据的主要来源。根据 2010-2017 年乌克兰主要血液学机构收集的数据，最污染地区成熟 B 细胞、急性髓系白血病和多发性骨髓瘤的发病率高于污染较少地区。首次根据乌克兰国家科学院 RE Kavetsky 实验病理学、肿瘤学和放射生物学研究所参考实验室编制的内部数据库，分析了 1997-2017 年期间几种特定类型白血病在总诊断血液系统恶性肿瘤中的相对贡献。2011-2017 年，参考实验室为大约 26%的乌克兰血液系统和淋巴组织肿瘤患者（不同形式的急性和慢性白血病患者的 34%）提供了诊断研究。切尔诺贝利事故后，受污染地区的总体白血病诊断病例中，急性髓系白血病和慢性淋巴细胞白血病的比例增加。
