W. Harry Feinstone Department of Molecular Microbiology and Immunology, Johns Hopkins Bloomberg School of Public Health, Baltimore MD, USA.
Biomedica. 2023 Aug 31;43(Sp. 1):267-277. doi: 10.7705/biomedica.6943.
Natural and human-made disasters have long played a role in shaping the environment and microbial communities, also affecting non-microbial life on Earth. Disaster microbiology is a new concept based on the notion that a disaster changes the environment causing adaptation or alteration of microbial populations -growth, death, transportation to a new area, development traits, or resistance- that can have downstream effects on the affected ecosystem. Such downstream effects include blooms of microbial populations and the ability to colonize a new niche or host, cause disease, or survive in former extreme conditions. Throughout history, fungal populations have been affected by disasters. There are prehistoric archeological records of fungal blooms after asteroid impacts and fungi implicated in the fall of the dinosaurs. In recent times, drought and dust storms have caused disturbance of soil fungi, and hurricanes have induced the growth of molds on wet surfaces, resulting in an increased incidence of fungal disease. Probably, the anticipated increase in extreme heat would force fungi adaptation to survive at high temperatures, like those in the human body, and thus be able to infect mammals. This may lead to a drastic rise of new fungal diseases in humans.
自然灾害和人为灾害长期以来一直对环境和微生物群落的形成起着重要作用,同时也影响着地球上的非微生物生命。灾害微生物学是一个新概念,它基于这样一种观念,即灾害会改变环境,导致微生物种群的适应或改变——生长、死亡、迁移到新的区域、发展特征或抗逆性——这可能会对受影响的生态系统产生下游影响。这种下游影响包括微生物种群的大量繁殖,以及能够在新的小生境或宿主中定殖、引起疾病或在以前的极端条件下生存的能力。纵观历史,真菌种群一直受到灾害的影响。有小行星撞击后真菌大量繁殖的史前考古记录,也有真菌导致恐龙灭绝的证据。在最近,干旱和沙尘暴导致土壤真菌受到干扰,飓风使潮湿表面上的霉菌生长,导致真菌感染的发病率上升。可能,预期的极端高温增加将迫使真菌适应在高温下生存,如在人体中,从而能够感染哺乳动物。这可能会导致人类新的真菌感染疾病急剧增加。