Roy R, Powers S R, Feustel P J, Dutton R E
Anesthesiology. 1977 Jun;46(6):385-90.
In ten supine anesthetized dogs, recordings of left atrial (LA) and pulmonary-artery wedge (PW) pressures were simultaneously obtained at several levels of positive end-expiratory pressure (PEEP) ventilation with the thorax either open or closed. Lateral roentgenograms were taken to determine the relative vertical positions of the LA and PW catheter tips. When the wedge catheter tip was vertically above the left artrial catheter tip, mean PW followed airway pressure at PEEP of more that 5 cm H20. For PEEP 5 cm H20 or less, and for PW catheter tip positions vertically below the LA catheter tip at all levels of PEEP, mean wedge catheter pressure was close to left atrial pressure. Thus, it appears the LA pressure can best be estimated by PW catheter positions vertically below the left atrium during positive end-expiratory pressure ventilation.
在十只仰卧位麻醉犬中，在呼气末正压（PEEP）通气的几个水平下，分别在胸腔开放和闭合的情况下，同时记录左心房（LA）和肺动脉楔压（PW）。拍摄侧位X线片以确定LA和PW导管尖端的相对垂直位置。当楔压导管尖端垂直于左心房导管尖端上方时，在呼气末正压大于5 cmH₂O时，平均PW跟随气道压力变化。对于呼气末正压为5 cmH₂O或更低时，以及在所有呼气末正压水平下楔压导管尖端垂直于左心房导管尖端下方的位置，平均楔压导管压力接近左心房压力。因此，在呼气末正压通气期间，似乎通过垂直于左心房下方的PW导管位置可以最好地估计左心房压力。
