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无症状患者的坏疽性穿孔性胆囊炎

Perforated Gangrenous Gallbladder in an Asymptomatic Patient.

作者信息

Faraji Mehdi, Sharp Rachel, Gutierrez Edgar, Malikayil Kiran, Sangi Ali

机构信息

Radiology, Louisiana State University Health Sciences Center, Shreveport, USA.

Family Medicine, Louisiana State University Health Sciences Center, Shreveport, USA.

出版信息

Cureus. 2020 Apr 18;12(4):e7728. doi: 10.7759/cureus.7728.

Abstract

Acute cholecystitis or inflammation of the gallbladder is a common cause of hospitalizations. A percentage of those patients will progress to gangrenous cholecystitis and perforation. This medical emergency can lead to peritonitis, which has increased morbidity and mortality. The first-line modality for the diagnosis of acute cholecystitis is an ultrasound, but if it is inconclusive, then a computed tomography (CT) scan may be beneficial. Gangrenous cholecystitis and perforation have been reported in asymptomatic diabetic patients secondary to diabetic neuropathy and/or gallbladder ischemia leading to nerve denervation. Yet, here we present the case of an asymptomatic non-diabetic patient with gangrenous gallbladder perforation that was treated with antibiotics and drain placements. Diagnosis and treatment involve the collaboration between primary care, interventional, and diagnostic services to appropriately manage these patients. This case demonstrates that clinicians should have a low threshold to conduct CT scan of the abdomen, especially when there is a sudden resolution of pain.

摘要

急性胆囊炎或胆囊炎症是住院治疗的常见病因。这些患者中有一定比例会进展为坏疽性胆囊炎和穿孔。这种医疗急症可导致腹膜炎,从而增加发病率和死亡率。急性胆囊炎诊断的一线检查手段是超声检查,但如果结果不明确,那么计算机断层扫描(CT)可能会有所帮助。已有报道称,无症状糖尿病患者会继发坏疽性胆囊炎和穿孔,原因是糖尿病神经病变和/或胆囊缺血导致神经去神经支配。然而,我们在此介绍一例无症状非糖尿病患者发生坏疽性胆囊穿孔的病例,该患者接受了抗生素治疗和引流管置入。诊断和治疗需要初级保健、介入和诊断服务部门之间的协作,以妥善管理这些患者。该病例表明,临床医生对进行腹部CT扫描的阈值应较低,尤其是在疼痛突然缓解的情况下。

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