Medicine School, Postgraduate Program in Public Health, Federal University of Minas Gerais, Belo Horizonte, Brazil.
Department of Odontology, Pontifical Catholic University of Minas Gerais, Belo Horizonte, Brazil.
PLoS One. 2020 May 20;15(5):e0233293. doi: 10.1371/journal.pone.0233293. eCollection 2020.
The hospitalizations are part of cancer care and has been studied by researchers worldwide. A better understanding about their associated factors may help to achieve improvements on this area. The aims of this study were to investigate the association between demographic and clinical characteristics and hospitalizations, as well as between these characteristics and the length of stay (LOS), within the first year of outpatient treatment, for the most incident cancers in the Brazilian population. In this cohort study, we investigated 417,477 patients aged 19 years or more, who started outpatient cancer treatment, from 2010-2014, for breast, prostate, colorectal, cervix, lung and stomach cancers. The outcomes evaluated were: i) Hospitalizations within the first year of outpatient cancer treatment; and ii) LOS of the hospitalized patients. It was performed a binary logistic regression to evaluate the association between the explanatory variables and the hospitalizations and a negative binomial regression to evaluate their influence on the length of hospital stay. The hospitalizations occurred for 34% of patients, with a median of LOS of 6 days (IQR: 2-15). Female patients were 16% less likely to be hospitalized (OR: 0.84; 95% CI: 0.82-0.86), with lower average of LOS (AR: 0.98; 95% CI: 0.97-0.99), each additional year of age reduced in 2% the hospitalization odds (OR: 0.98; 95% CI: 0.98-0.99) and in 1% the average of LOS (AR: 0.99; 95% CI: 0.98-0.99), patients from South region had twice more chances of hospitalization than from North region (OR: 2.01; 95% CI: 1.93-2.10) and patients with colorectal cancer had greater probability of hospitalization (OR: 4.42; 95% CI: 4.27-4.48), with the highest average of LOS (AR: 1.37; 95% CI: 1.35-1.40). In view of our results, we consider that the government must expand the policies with potential to reduce the number of hospitalizations.
住院治疗是癌症治疗的一部分，已被世界各地的研究人员进行了研究。更好地了解其相关因素可能有助于改善这一领域。本研究的目的是调查人口统计学和临床特征与住院治疗之间的关系，以及这些特征与首次门诊治疗后一年内的住院时间（LOS）之间的关系，针对巴西人群中最常见的癌症。在这项队列研究中，我们调查了 2010 年至 2014 年间，年龄在 19 岁及以上的 417477 名开始门诊癌症治疗的患者，他们患有乳腺癌、前列腺癌、结直肠癌、宫颈癌、肺癌和胃癌。评估的结果是：i）首次门诊癌症治疗后一年内的住院治疗；ii）住院患者的 LOS。进行了二元逻辑回归以评估解释变量与住院治疗之间的关系，以及负二项回归以评估它们对住院时间的影响。34%的患者需要住院治疗，中位 LOS 为 6 天（IQR：2-15）。女性患者住院的可能性降低 16%（OR：0.84；95%CI：0.82-0.86），平均 LOS 降低 0.98（AR：0.97-0.99），每增加 1 岁，住院的几率降低 2%（OR：0.98；95%CI：0.98-0.99），平均 LOS 降低 1%（AR：0.99；95%CI：0.98-0.99），来自南部地区的患者住院的可能性是来自北部地区的两倍（OR：2.01；95%CI：1.93-2.10），患有结直肠癌的患者有更高的住院可能性（OR：4.42；95%CI：4.27-4.48），LOS 最长（AR：1.37；95%CI：1.35-1.40）。鉴于我们的结果，我们认为政府必须扩大政策，以减少住院人数。
