NIHR Nottingham Biomedical Research Centre.
Division of Clinical Neuroscience, School of Medicine, University of Nottingham.
Trends Hear. 2020 Jan-Dec;24:2331216520918416. doi: 10.1177/2331216520918416.
Tinnitus is the perception of sound in the absence of a corresponding external sound source, and bothersome tinnitus has been linked to poorer cognitive performance. This review comprehensively quantifies the association between tinnitus and different domains of cognitive performance. The review protocol was preregistered and published in a peer-reviewed journal. The review and analyses were reported according to Preferred Reporting Items for Systematic Review and Meta-analysis guidelines. Peer-reviewed literature was searched using electronic databases to find studies featuring participants with tinnitus who had undertaken measures of cognitive performance. Studies were assessed for quality and categorized according to an established cognitive framework. Random-effects meta-analyses were performed on various cognitive domains with potential moderator variables assessed where possible. Thirty-eight records were included in the analysis from a total of 1,863 participants. Analyses showed that tinnitus is associated with poorer executive function, processing speed, general short-term memory, and general learning and retrieval. Narrow cognitive domains of Inhibition and Shifting (within executive function) and learning and retrieval (within general learning and retrieval) were also associated with tinnitus.
耳鸣是指在没有相应外部声源的情况下感知到声音，而烦人的耳鸣与认知表现较差有关。本综述全面量化了耳鸣与认知表现不同领域之间的关联。综述方案已预先注册并发表在同行评审期刊上。综述和分析报告符合系统评价和荟萃分析指南的首选报告项目。使用电子数据库搜索同行评审文献，以找到对有耳鸣的参与者进行认知表现测量的研究。根据既定的认知框架评估研究的质量并进行分类。在可能的情况下，对各种认知领域进行了随机效应荟萃分析，并评估了潜在的调节变量。从总共 1863 名参与者中，有 38 份记录被纳入分析。分析表明，耳鸣与执行功能、处理速度、一般短期记忆以及一般学习和检索能力较差有关。抑制和转换（在执行功能内）以及学习和检索（在一般学习和检索内）等狭窄的认知领域也与耳鸣有关。
