Department of Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China;Chun-Shuang Guan and Lian-Gui Wei contributed equally to this work.
Department of Radiology, Beijing Ditan Hospital, Capital Medical University, Beijing, China.
Diagn Interv Radiol. 2020 Jul;26(4):301-307. doi: 10.5152/dir.2019.20176.
We aimed to retrospectively analyze the imaging changes detected in the follow-up of coronavirus disease 2019 (COVID-19) patients on thin-section computed tomography (CT).
We included 54 patients diagnosed with COVID-19. The mean interval between the initial and follow-up CT scans was 7.82±3.74 days. Patients were divided into progression and recovery groups according to their outcomes. We evaluated CT images in terms of distribution of lesions and imaging manifestations. The manifestations included ground-glass opacity (GGO), crazy-paving pattern, consolidation, irregular line, and air bronchogram sign.
COVID-19 lesions showed mainly subpleural distribution, which was accompanied by bronchovascular bundle distribution in nearly 30% of the patients. The lower lobes of both lungs were the most commonly involved. In the follow-up, the progression group showed more involvement of the upper lobe of the left lung than the recovery group. GGO was the most common sign. As the disease progressed, round GGO decreased and patchy GGO increased. On follow-up CT, consolidation increased in the progression group while decreasing in the recovery group. Air bronchogram sign was more commonly observed at the initial examination (90.9%) than at follow-up (30%) in the recovery group, but there was no significant change in the progression group. Pleural effusion and lymphadenopathy were absent in the initial examination, but pleural effusion was observed in three cases after follow-up.
As COVID-19 progressed, round GGOs tended to evolve into patchy GGOs, consolidation increased, and pleural effusion could be occasionally observed. As COVID-19 resolved, the crazy-paving pattern and air bronchogram significantly decreased.
本研究旨在回顾性分析新型冠状病毒肺炎(COVID-19)患者在薄层计算机断层扫描(CT)随访中的影像学改变。
本研究纳入了 54 例确诊为 COVID-19 的患者。首次 CT 扫描与随访 CT 扫描的平均间隔时间为 7.82±3.74 天。根据患者的转归,将其分为进展组和恢复组。我们评估了 CT 图像中病变的分布和影像学表现。这些表现包括磨玻璃影(GGO)、铺路石征、实变、不规则线和空气支气管征。
COVID-19 病变主要呈胸膜下分布,近 30%的患者伴有支气管血管束分布。双肺下叶最常受累。在随访中,进展组左肺上叶的受累程度高于恢复组。GGO 是最常见的表现。随着病情的进展,圆形 GGO 减少,斑片状 GGO 增多。在随访 CT 上,进展组的实变增加,而恢复组的实变减少。空气支气管征在恢复组的初始检查中(90.9%)比随访时(30%)更常见,但在进展组中没有明显变化。在初始检查中未见胸腔积液和淋巴结肿大,但在随访中有 3 例出现胸腔积液。
随着 COVID-19 的进展,圆形 GGO 倾向于演变为斑片状 GGO,实变增加,偶尔可观察到胸腔积液。随着 COVID-19 的恢复,铺路石征和空气支气管征显著减少。