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使用三维猪胶原基质联合冠向推进瓣治疗米勒I型和II型牙龈退缩缺损:一项随机临床半口试验(1年随访)

Treatment of miller type I and II gingival recession defects using three-dimensional porcine collagen matrix with coronally advanced flap: A randomized clinical split-mouth trial (a 1-year follow-up).

作者信息

Barakat Haydar, Dayoub Suleiman

机构信息

Department of Periodontology, Dental Faculty, Damascus University, Damascus, Syria.

出版信息

Indian J Dent Res. 2020 Mar-Apr;31(2):209-216. doi: 10.4103/ijdr.IJDR_897_18.

DOI:10.4103/ijdr.IJDR_897_18
PMID:32436899
Abstract

INTRODUCTION

The main goal of periodontal plastic surgery is obtaining complete root coverage (CRC) and an optimal appearance.

AIM

The aim of this study was to evaluate the effectiveness of a three-dimensional porcine collagen matrix (PCM) with coronally advanced flap (CAF) in treating of Miller type I and II gingival recession (GR).

MATERIALS AND METHODS

Twenty patients were enrolled in this study, presenting 40 Miller type I and II GR. Patients were randomized into test group (PCM + CAF) and control group [connective tissue graft (CTG + CAF)]. Clinical parameters such as recession depth (RD), probing depth, clinical attachment level (CAL), and width of keratinized gingiva (WKG) were evaluated at baseline and 12 months later. Root coverage percentage (RC%) and CRC were assessed at 12 months post surgically. Statistical analysis was performed using independent t-test for intergroup comparison. Statistical significance was set at 0.05.

RESULTS

The mean RD at 12 months was 0.20 mm for the test group and 0.12 mm for the control group, whereas the mean RC% was 94.22% for PCM + CAF and 96.48% for CTG + CAF. CRC was higher in CTG + CAF with 80%. CAL gain was 2.05 and 2.07 mm in the test and control sites, respectively. The gain of WKG was 1.35 and 1.30 mm in the test and control sites, respectively. Patient esthetic satisfaction at 12 months post surgically in both groups was equivalent.

CONCLUSION

Within the limits of this study, using of PCM + CAF in treating GR is a successful and effective treatment option and could serve as an alternative to CTGs.

摘要

引言

牙周整形手术的主要目标是实现完全的牙根覆盖(CRC)并获得理想外观。

目的

本研究旨在评估三维猪胶原蛋白基质(PCM)联合冠向推进瓣(CAF)治疗Miller I型和II型牙龈退缩(GR)的有效性。

材料与方法

本研究纳入20例患者,共出现40处Miller I型和II型GR。患者被随机分为试验组(PCM + CAF)和对照组[结缔组织移植(CTG + CAF)]。在基线时和12个月后评估临床参数,如退缩深度(RD)、探诊深度、临床附着水平(CAL)和角化龈宽度(WKG)。术后12个月评估牙根覆盖百分比(RC%)和完全牙根覆盖情况。采用独立t检验进行组间比较的统计分析。设定统计学显著性水平为0.05。

结果

试验组术后12个月的平均RD为0.20 mm,对照组为0.12 mm,而PCM + CAF组的平均RC%为94.22%,CTG + CAF组为96.48%。CTG + CAF组的完全牙根覆盖率更高,为80%。试验组和对照组位点的CAL增加分别为2.05和2.07 mm。试验组和对照组位点的WKG增加分别为1.35和1.30 mm。两组术后12个月患者的美学满意度相当。

结论

在本研究的范围内,使用PCM + CAF治疗GR是一种成功且有效的治疗选择,可作为结缔组织移植的替代方法。

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