Department of Evidence-based Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China; Shanghai Medical Aid Team in Wuhan, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
Department of Evidence-based Medicine, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China; Shanghai Medical Aid Team in Wuhan, Shanghai General Hospital, Shanghai Jiao Tong University, School of Medicine, Shanghai, China.
J Clin Virol. 2020 Jul;128:104396. doi: 10.1016/j.jcv.2020.104396. Epub 2020 Apr 29.
Since the outbreak of novel coronavirus disease 2019 (COVID-19), epidemic prevention strategies have been implemented worldwide. For the sake of controlling the infectious coronavirus pneumonia, early diagnosis and quarantine play an imperative role. Currently, the mainstream diagnostic methods are imaging and laboratory diagnosis, which differ in their efficacy of diagnosis. To compare the detection rate, we reviewed numerous literature on pneumonia caused by coronaviruses (SARS, MERS, and SARS-CoV-2) and analyzed two different ways of diagnosis. The results showed that the detection rate of computed tomography (CT) diagnosis was significantly higher than that of real-time quantitative polymerase chain reaction (qPCR) (P = 0.00697). Still, clinicians should combine radiology and laboratory methods to achieve a higher detection rate, so that instant isolation and treatment could be effectively conducted to curb the rampant spread of the epidemic.
自 2019 年新型冠状病毒病（COVID-19）爆发以来，全球已实施了防疫策略。为了控制传染性冠状病毒肺炎，早期诊断和隔离起着至关重要的作用。目前，主流的诊断方法是影像学和实验室诊断，它们在诊断效果上有所不同。为了比较检测率，我们查阅了大量关于冠状病毒（SARS、MERS 和 SARS-CoV-2）引起的肺炎的文献，并分析了两种不同的诊断方法。结果表明，计算机断层扫描（CT）诊断的检测率明显高于实时荧光定量聚合酶链反应（qPCR）（P=0.00697）。尽管如此，临床医生仍应结合影像学和实验室方法以提高检测率，从而可以有效地进行即时隔离和治疗，以遏制疫情的肆虐传播。
