District Public Health Authority, Montabaur, Germany.
District Public Health Authority, Trier, Germany.
Euro Surveill. 2020 Jul;25(30). doi: 10.2807/1560-7917.ES.2020.25.30.2001292.
We analysed consecutive RT-qPCR results of 537 symptomatic coronavirus disease (COVID-19) patients in home quarantine. Respectively 2, 3, and 4 weeks after symptom onset, 50%, 25% and 10% of patients had detectable RNA from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2). In patients with mild COVID-19, RNA detection is likely to outlast currently known periods of infectiousness by far and fixed time periods seem more appropriate in determining the length of home isolation than laboratory-based approaches.
我们分析了 537 例在家隔离的有症状的冠状病毒病(COVID-19)患者的连续 RT-qPCR 结果。分别在症状出现后 2、3 和 4 周,50%、25%和 10%的患者可检测到严重急性呼吸综合征冠状病毒-2(SARS-CoV-2)的 RNA。在轻症 COVID-19 患者中,RNA 检测可能远远超过目前已知的传染性期,并且与基于实验室的方法相比,固定时间段似乎更适合确定居家隔离的时间。