Geneva School of Health Sciences, HES-SO University of Applied Sciences and Arts Western Switzerland, Geneva, Switzerland.
Department of Epidemiology, Research Line Functioning and Rehabilitation, CAPHRI, Maastricht University, Maastricht, the Netherlands.
Clin Interv Aging. 2020 May 7;15:645-654. doi: 10.2147/CIA.S246998. eCollection 2020.
BACKGROUND/OBJECTIVES: Early detection of fall risk in persons older than 65 is of clinical relevance, but the diagnostic accuracy of currently used functional tests (eg short physical performance battery [SPPB] and timed up and go test [TUG]) to assess older persons' fall risks remains moderate. Recent literature highlights the importance of strong hip abductors to prevent falls. We thus aimed to assess the diagnostic accuracy of hip abductor strength measures to assess older persons' fall risks.
Hip abductor maximum voluntary isometric strength (ABD MVIS), rate of force generation (ABD RFG), and the SPPB and TUG functional fall risk assessments were assessed in 60 persons aged over 65 years (82.0 ± 6.1 years). The diagnostic accuracy (area under the curve [AUC], sensitivity [sens], specificity [spec], positive predictive value [PPV], negative predictive value [NPV], and positive and negative likelihood ratios [LR, LR]) was evaluated at a clinically important 90% sensitivity level. Cut-off values for clinical use were calculated.
In our population, hip ABD MVIS (AUC 0.8, sens 90.6%, spec 57.1%, PPV 70.7%, NPV 84.2%, LR+ 2.1, LR- 0.2, and cut-off value ≤ 1.1 N/kg) and hip ABD RFG (AUC 0.8, sens 90.6%, spec 46.4%, PPV 65.9%, NPV 81.3%, LR+ 1.7, LR- 0.2, and cut-off ≤ 8.47 N/kg/s) show diagnostic accuracy comparable to other fall risk assessments (SPPB and TUG) and a high net sensitivity when used in a test battery.
Hip ABD MVIS or RFG shows good diagnostic accuracy to differentiate between older fallers and nonfallers compared to the chosen external criterion history of falls. The high net sensitivity when hip ABD MVIS or RFG is combined with currently used fall risk assessments shows promise in contributing value to a test battery and should be investigated further in longitudinal studies.
背景/目的:65 岁以上人群的跌倒风险的早期检测具有临床意义,但目前用于评估老年人跌倒风险的功能性测试(如短体物理表现电池[SPPB]和计时起立行走测试[TUG])的诊断准确性仍然不高。最近的文献强调了强大的髋关节外展肌对预防跌倒的重要性。因此,我们旨在评估髋关节外展肌力测量评估老年人跌倒风险的诊断准确性。
评估了 60 名年龄在 65 岁以上的人的髋关节外展肌最大自主等长力量(ABD MVIS)、力量生成率(ABD RFG)以及 SPPB 和 TUG 功能性跌倒风险评估。在具有临床意义的 90%敏感性水平下评估了诊断准确性(曲线下面积[AUC]、敏感性[sens]、特异性[spec]、阳性预测值[PPV]、阴性预测值[NPV]、阳性和阴性似然比[LR、LR-])。计算了临床使用的截断值。
在我们的人群中,髋关节 ABD MVIS(AUC 0.8,sens 90.6%,spec 57.1%,PPV 70.7%,NPV 84.2%,LR+ 2.1,LR- 0.2,截断值≤1.1 N/kg)和髋关节 ABD RFG(AUC 0.8,sens 90.6%,spec 46.4%,PPV 65.9%,NPV 81.3%,LR+ 1.7,LR- 0.2,截断值≤8.47 N/kg/s)与其他跌倒风险评估(SPPB 和 TUG)相比具有相当的诊断准确性,并且在测试组合中使用时具有高的净敏感性。
与所选外部标准(跌倒史)相比,髋关节 ABD MVIS 或 RFG 显示出区分跌倒者和非跌倒者的良好诊断准确性。当髋关节 ABD MVIS 或 RFG 与目前使用的跌倒风险评估相结合时,高的净敏感性具有在测试组合中提供价值的潜力,应该在纵向研究中进一步研究。