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全球结核病发病率与世界卫生组织终止结核病战略首个里程碑之间的差距:基于2017年全球疾病负担数据库的分析

The Gap Between Global Tuberculosis Incidence and the First Milestone of the WHO End Tuberculosis Strategy: An Analysis Based on the Global Burden of Disease 2017 Database.

作者信息

Pan Zhenyu, Zhang Jun, Bu Qingting, He Hairong, Bai Ling, Yang Jin, Liu Qingqing, Lyu Jun

机构信息

Clinical Research Center, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, People's Republic of China.

School of Public Health, Xi'an Jiaotong University Health Science Center, Xi'an, Shaanxi, People's Republic of China.

出版信息

Infect Drug Resist. 2020 May 4;13:1281-1286. doi: 10.2147/IDR.S248875. eCollection 2020.

Abstract

OBJECTIVE

The first milestone (in 2020) of the End Tuberculosis (TB) Strategy of the World Health Organization was a 20% reduction in TB incidence rate compared with the 2015 baseline. This study aimed to determine the incidence rate of TB and how it has changed since 2015 at the global, regional, and country levels.

METHODS

This study used the most recent data from the Global Burden of Disease study in 2017 to extract TB incidence rates at the global, regional, and country levels. The annual percentage change in the incidence rate (APCIR) of TB based on 2015 was calculated to evaluate the trend in the changes at various levels, including globally and at the regional and country levels. An APCIR of -4% from 2015 to 2020 is considered acceptable.

RESULTS

The global APCIR was only -1.1% from 2015 to 2017. Only 2 of the 21 analyzed regions had APCIRs lower than -4%: Southern Sub-Saharan Africa and Eastern Europe. Worse still, six regions exhibited increasing TB incidence rates. At the country level, although 143 of 195 countries and territories showed reductions in TB incidence rates, the APCIR was lower than -4% in only 11 of them.

CONCLUSION

This study suggests that it will be difficult to achieve the 2020 incidence rate milestone of the End Tuberculosis Strategy. This indicates the need to design and implement suitable strategies to address the current situation in order to achieve the next milestone and targets of the End Tuberculosis Strategy.

摘要

目的

世界卫生组织终止结核病战略的首个里程碑(2020年)是结核病发病率相较于2015年基线水平降低20%。本研究旨在确定全球、区域和国家层面的结核病发病率及其自2015年以来的变化情况。

方法

本研究使用了2017年全球疾病负担研究的最新数据,以提取全球、区域和国家层面的结核病发病率。计算基于2015年的结核病发病率年度百分比变化(APCIR),以评估包括全球、区域和国家层面在内的各层面变化趋势。2015年至2020年期间APCIR为-4%被视为可接受。

结果

2015年至2017年全球APCIR仅为-1.1%。在分析的21个区域中,只有2个区域的APCIR低于-4%:撒哈拉以南非洲南部和东欧。更糟糕的是,有6个区域的结核病发病率呈上升趋势。在国家层面,尽管195个国家和地区中有143个的结核病发病率有所下降,但其中只有11个的APCIR低于-4%。

结论

本研究表明,实现终止结核病战略2020年发病率里程碑将很困难。这表明需要设计和实施合适的策略来应对当前形势,以实现终止结核病战略的下一个里程碑和目标。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20d7/7210037/ba557b86c3a2/IDR-13-1281-g0001.jpg

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