Zhang Lin-Hua, Chen Gang, Tao Wei
Department of Ultrasound.
Department of Radiology, Ningbo Municipal Hospital of TCM, Ningbo, China.
Medicine (Baltimore). 2020 May;99(20):e20180. doi: 10.1097/MD.0000000000020180.
Previous clinical studies have reported that clinical value of high-frequency ultrasound combined computed tomography (HFUCT) is used for diagnosis of thyroid tumor (TT). However, no study has investigated this topic systematically. Therefore, this study will evaluate the clinical value of HFUCT for the diagnosis of TT.
We will search the databases of Cochrane Library, EMBASE, PUBMED, SCOPUS, Web of Science, OpenGrey, Cumulative Index to Nursing and Allied Health Literature, Allied and Complementary Medicine Database, and China National Knowledge Infrastructure from any time period published to the present. We will consider all case-controlled studies that assessed the clinical value of HFUCT for diagnosis of TT. Two authors will independently scan titles and abstracts to check eligible studies, followed by full-text read. We will extract data and assess study quality using Quality Assessment of Diagnostic Accuracy Studies tool. RevMan 5.3 software will be utilized for data pooling and statistical analysis.
This study will be performed to assess the clinical value of HFUCT for the diagnosis of TT, and will provide an evidence-based synthesis for clinical application and further study.
Summary of this study will provide the latest evidence to determine whether HFUCT can be used for TT diagnosis accurately.
INPLASY202040022.
以往临床研究报道了高频超声联合计算机断层扫描（HFUCT）用于诊断甲状腺肿瘤（TT）的临床价值。然而，尚无研究对此主题进行系统调查。因此，本研究将评估HFUCT对TT的诊断价值。
我们将检索Cochrane图书馆、EMBASE、PUBMED、SCOPUS、科学网、OpenGrey、护理学与健康照护文献累积索引、补充与替代医学数据库以及中国知网等数据库，检索时间范围为从创刊至当前。我们将纳入所有评估HFUCT对TT诊断临床价值的病例对照研究。两名作者将独立筛查标题和摘要以检查符合条件的研究，随后进行全文阅读。我们将使用诊断准确性研究质量评估工具提取数据并评估研究质量。将使用RevMan 5.3软件进行数据合并和统计分析。
本研究将评估HFUCT对TT的诊断价值，并为临床应用和进一步研究提供循证综合分析。
本研究总结将提供最新证据，以确定HFUCT是否可准确用于TT诊断。
INPLASY202040022。
