玻璃体内注射地塞米松植入物治疗难治性成人科茨病：一例报告。
Refractory adult Coats disease treated with dexamethasone intravitreal implant: A case report.
作者信息
Ding Yu-Hua, Yao Bang-Tao, Zhao Xiao-Gui, Yu Hao, Liu Gang, Wang Xiu-Ying
机构信息
Department of Ophthalmology, Jiangsu Province Hospital, The First Affiliated Hospital of Nanjing Medical University.
Department of Ophthalmology, Lishui District People's Hospital, Lishui branch of Southeast University Affiliated Zhongda Hospital, Nanjing, Jiangsu Province, China.
出版信息
Medicine (Baltimore). 2020 May;99(20):e20249. doi: 10.1097/MD.0000000000020249.
INTRODUCTION
Coats disease is a sporadic, retinal vascular abnormality, causing blindness. Several interventional methods, including laser photocoagulation, have been proposed; however, the use of intravitreal dexamethasone in refractory Coats disease is not well described.
PATIENT CONCERNS
A 38-year-old man presented with a painless reduction in visual acuity in his right eye, commencing 15 days prior to initial assessment.
DIAGNOSIS
Clinical manifestations and multimodal imaging indicated Coats disease.
INTERVENTIONS
Retinal laser photocoagulation was performed in the nonperfused areas, 15 months later, the exudative retinal detachment, and macular edema remained, the patient was then treated with an intravitreal slow-release dexamethasone implant.
OUTCOMES
The exudative retinal detachment and macular edema had resolved, and the BCVA had also improved.
CONCLUSION
Dexamethasone intravitreal implantation was effective in treating refractory Coats disease.
引言
科茨病是一种散发性视网膜血管异常疾病，可导致失明。已经提出了几种干预方法，包括激光光凝；然而，玻璃体内注射地塞米松在难治性科茨病中的应用尚无详细描述。
患者情况
一名38岁男性，在初次评估前15天开始出现右眼无痛性视力下降。
诊断
临床表现和多模式成像显示为科茨病。
干预措施
在无灌注区进行视网膜激光光凝，15个月后，视网膜渗出性脱离和黄斑水肿仍然存在，随后患者接受了玻璃体内缓释地塞米松植入治疗。
结果
视网膜渗出性脱离和黄斑水肿消退，最佳矫正视力也有所改善。
结论
玻璃体内植入地塞米松治疗难治性科茨病有效。
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