Eye Center, 117921Renmin Hospital of Wuhan University, Wuhan, P.R. China.
Eur J Ophthalmol. 2021 May;31(3):1177-1184. doi: 10.1177/1120672120926453. Epub 2020 May 26.
The appearance of the far peripheral retina in normal eyes was observed using an Optos ultra-wide field fluorescein angiography imaging system.
A cross-sectional study of ultra-wide field pseudocolor and angiography images obtained using the Optos 200Tx. Four different non-vascular and six vascular-associated fluorescence features in far peripheral retina were analyzed.
A total of 166 eyes in 83 patients met the inclusion criteria. The mean patient age was 40.78 ± 10.94 years (range: 20-65 years) with a female-to-male ratio of 0.98. Slight cataract were present in 64 eyes (38.55%), low to moderate myopia in 50 eyes (30.12%), and unspecified visual disturbances in 52 eyes (31.33%). Far peripheral retinas were found to have mottled florescent band in 42.17% eyes, ground glass hyperfluorescence in 84.34% eyes, granular hyperfluorescence in 12.65% eyes, local mottled fluorescence in 10.84% eyes, vascular anastomosis with a peripheral avascular area in 36.23% eyes, invisible capillary details in 50.67% eyes, vessels passing through the ora serrata in 16.98% eyes, late-phase slight leakage in 32.53% eyes, angiectasis in 18.67% eyes, and microaneurysm in 34.94% eyes.
Ultra-wide field fluorescein angiography revealed various fluorescence features in the periphery of normal eyes, providing a basis for interpreting normal and pathological changes in peripheral retina and an important reference for clinical work.
使用 Optos 超广角荧光素血管造影成像系统观察正常眼的远周边部视网膜外观。
对 Optos 200Tx 获得的超广角假彩色和血管造影图像进行横断面研究。分析远周边部视网膜的 4 种非血管和 6 种与血管相关的荧光特征。
共有 83 例患者的 166 只眼符合纳入标准。患者平均年龄为 40.78±10.94 岁（范围：20-65 岁），女性与男性比例为 0.98。64 只眼（38.55%）存在轻度白内障，50 只眼（30.12%）存在低度至中度近视，52 只眼（31.33%）存在未特指的视力障碍。42.17%的远周边部视网膜出现斑驳荧光带，84.34%的远周边部视网膜出现磨砂玻璃样高荧光，12.65%的远周边部视网膜出现颗粒状高荧光，10.84%的远周边部视网膜出现局部斑驳荧光，36.23%的远周边部视网膜出现血管吻合伴周边无血管区，50.67%的远周边部视网膜出现不可见毛细血管细节，16.98%的远周边部视网膜出现血管穿过锯齿缘，32.53%的远周边部视网膜出现晚期轻微渗漏，18.67%的远周边部视网膜出现血管扩张，34.94%的远周边部视网膜出现微动脉瘤。
超广角荧光素血管造影显示正常眼周边存在多种荧光特征，为解释周边视网膜的正常和病理改变提供了依据，为临床工作提供了重要参考。
