Tedla Weldegebrial Hayelom, Aregay Alemseged, Gebremariam Kidanu, Abrha Mulugeta Woldu, Weldearegay Haftom Gebrehiwot
Mekelle General Hospital, Mekelle, Ethiopia.
Mekelle University, College of Health Sciences, Mekelle, Ethiopia.
J Nutr Metab. 2020 Apr 23;2020:9858619. doi: 10.1155/2020/9858619. eCollection 2020.
HIV/AIDS and malnutrition are interrelated and exacerbate one another in a vicious cycle. As HIV infection progresses it causes catabolic state and increases susceptibility to other infections, leading to progressive aggravation of undernutrition. However, data are lacking in Ethiopia on determinants of undernutrition among people living with HIV on antiretroviral therapy. Therefore, this study aimed to assess determinants of undernutrition among adult HIV/AIDS patients in Northern Ethiopia.
Facility-based unmatched case-control study was conducted among 324 randomly selected people living with HIV on antiretroviral therapy (ART). A structured and pretested interviewer questionnaire was used to collect data, while digital Seca weight and Seca measuring rod were used to measure weight and height, respectively. Logistic regression was used to identify independent factors of undernutrition, and value <0.05 was declared for statistical significance. All statistical analyses were performed using SPSS 21™.
This study revealed that people of younger age and those on ART (AOR = 0.29 (95% CI: 0.10, 0.84)) had low risk of being undernourished. However, average individual monthly income (AOR = 2.61 (95% CI: 1.48, 4.61)), not receiving nutritional counseling during visits (AOR = 2.5 (95% CI: 1.52-3.89)), and low diet diversity (AOR = 10.55 (95% CI: 4.17, 26.73)) had higher odds of undernutrition among people living with HIV/AIDS.
Age of patients, average monthly income, nutritional counseling during visits, and diet diversity were the independent factors of undernutrition. Counseling on well-timed and sufficient consumption of nutritious foods, economic strengthening, and livelihood activities is important. Future longitudinal study is necessary to elucidate the problem of undernutrition among people living with HIV/AIDS.
艾滋病毒/艾滋病与营养不良相互关联,形成恶性循环,相互加剧。随着艾滋病毒感染的进展,会导致分解代谢状态,并增加对其他感染的易感性,从而导致营养不良逐渐加重。然而,埃塞俄比亚缺乏关于接受抗逆转录病毒治疗的艾滋病毒感染者中营养不良决定因素的数据。因此,本研究旨在评估埃塞俄比亚北部成年艾滋病毒/艾滋病患者中营养不良的决定因素。
在324名随机选择的接受抗逆转录病毒治疗(ART)的艾滋病毒感染者中进行了基于机构的非匹配病例对照研究。使用结构化且经过预测试的访谈问卷收集数据,同时分别使用数字赛卡体重秤和赛卡测量杆测量体重和身高。采用逻辑回归确定营养不良的独立因素,P值<0.05被视为具有统计学意义。所有统计分析均使用SPSS 21™进行。
本研究表明,年龄较小的人和接受抗逆转录病毒治疗的人(调整后比值比[AOR]=0.29(95%置信区间:0.10,0.84))营养不良风险较低。然而,平均个人月收入(AOR=2.61(95%置信区间:1.48,4.61))、就诊期间未接受营养咨询(AOR=2.5(95%置信区间:1.52 - 3.89))以及饮食多样性低(AOR=10.55(95%置信区间:4.17,26.73))在艾滋病毒/艾滋病感染者中营养不良的几率较高。
患者年龄、平均月收入、就诊期间的营养咨询以及饮食多样性是营养不良的独立因素。就及时和充足食用营养丰富的食物、增强经济实力和生计活动进行咨询很重要。未来有必要进行纵向研究以阐明艾滋病毒/艾滋病感染者中的营养不良问题。