头孢唑林预防胆囊切除术后伤口脓毒症的应用
Prophylactic use of cephazolin against wound sepsis after cholecystectomy.
作者信息
Strachan C J, Black J, Powis S J, Waterworth T A, Wise R, Wilkinson A R, Burdon D W, Severn M, Mitra B, Norcott H
出版信息
Br Med J. 1977 May 14;1(6071):1254-6. doi: 10.1136/bmj.1.6071.1254.
Abstract
A trial of antibiotic prophylaxis with cephazolin against postoperative wound sepsis was carried out on 201 patients undergoing routine cholecystectomy. Wound sepsis occurred in 11 out of 65 controls (16.9%), who were not given the drug; two out of 63 patients (3.2%) given a single dose preoperatively; and four out of 73 patients (5.5%) given the single preoperative dose plus a five-day course postoperatively. The difference between the controls and patients given the single preoperative dose was significant.
摘要
对201例行常规胆囊切除术的患者进行了一项使用头孢唑林预防术后伤口感染的试验。65名未使用该药物的对照组患者中有11人（16.9%）发生伤口感染；63名术前接受单剂量药物治疗的患者中有2人（3.2%）发生感染；73名术前接受单剂量药物治疗且术后接受为期五天疗程治疗的患者中有4人（5.5%）发生感染。对照组与术前接受单剂量药物治疗的患者之间的差异具有统计学意义。
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本文引用的文献
1
AMPICILLIN LEVELS IN HUMAN BILE.人体胆汁中的氨苄青霉素水平。
Br J Pharmacol Chemother. 1965 Feb;24(1):189-93. doi: 10.1111/j.1476-5381.1965.tb02094.x.
2
3
Rifamide in acute cholecystitis and biliary surgery.利福酰胺在急性胆囊炎及胆道手术中的应用
Br Med J. 1971 Jul 31;3(5769):284-7. doi: 10.1136/bmj.3.5769.284.
4
Clinical studies of cefazolin in the surgical field.头孢唑林在外科领域的临床研究。
Antimicrob Agents Chemother (Bethesda). 1970;10:467-72.
5
An endogenous source for wound infections based on quantitative bacteriology of the biliary tract.
Surgery. 1970 Sep;68(3):471-6.
6
Postoperative wound infection: a prospective study of determinant factors and prevention.术后伤口感染：决定因素与预防的前瞻性研究
Surgery. 1969 Jul;66(1):97-103.
7
Bacteriology and antibiotic selection in biliary tract surgery.胆道手术中的细菌学与抗生素选择
Arch Surg. 1968 Oct;97(4):533-7. doi: 10.1001/archsurg.1968.01340040029002.
8
Levels of cefazolin in human bile.
J Infect Dis. 1973 Oct;128:Suppl:S361-3. doi: 10.1093/infdis/128.supplement_2.s361.
9
The significance of infection in biliary disease.感染在胆道疾病中的意义。
J R Coll Surg Edinb. 1973 Jul;18(4):209-12.
10
The effect of a single-dose parenteral antibiotic in the prevention of wound infection. A controlled trial.单剂量胃肠外抗生素预防伤口感染的效果：一项对照试验。
Br J Surg. 1972 Feb;59(2):98-9. doi: 10.1002/bjs.1800590206.
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