Gu Huaxin, Wei Shuaishuai, Hu Menghong, Wei Huang, Wang Xinghuo, Shang Yueyong, Li Li'ang, Shi Huahong, Wang Youji
International Research Center for Marine Biosciences, Ministry of Science and Technology, Shanghai Ocean University, Shanghai, 201306, China; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, Shanghai, 201306, China.
International Research Center for Marine Biosciences, Ministry of Science and Technology, Shanghai Ocean University, Shanghai, 201306, China; Key Laboratory of Exploration and Utilization of Aquatic Genetic Resources, Ministry of Education, Shanghai Engineering Research Center of Aquaculture, Shanghai Ocean University, Shanghai, 201306, China.
J Hazard Mater. 2020 Nov 5;398:122909. doi: 10.1016/j.jhazmat.2020.122909. Epub 2020 May 13.
The highly hydrophobic surfaces make microplastics a potential carrier of organic pollutants in the marine environment. In order to explore the toxic effects of polybrominated diphenyl ethers (BDE-47) combined with microplastics on marine organisms, we exposed the marine mussel Mytilus coruscus to micro-PS combined with BDE-47 for 21 days to determine the immune defense, oxidative stress and energy metabolism of the mussels. The results showed that the clearance rate (CR) of mussels exposed to single micro-PS, single BDE-47 or both was lower than control group. In general, compared to single BDE-47 exposure, the combination of micro-PS and BDE-47 significantly increased respiration rate (RR), activities of acid phosphatase (ACP) and alkaline phosphatase (ALP), reactive oxygen species (ROS) production and malondialdehyde (MDA) concentrations, but significantly decreased lactate dehydrogenase (LDH) activity and the relative expression of heat shock protein (Hsp70 and 90). Overall, combined stress has more adverse effects on defense performance and energy metabolism in mussels and micro-PS seem to exacerbate the toxicological effects of BDE-47. As microplastics pollution may deteriorate in the future, the health of mussels may be threatened in organically polluted environment, which eventually change the stability of the structure and function of intertidal ecosystem.
高度疏水的表面使微塑料成为海洋环境中有机污染物的潜在载体。为了探究多溴二苯醚（BDE - 47）与微塑料联合作用对海洋生物的毒性效应，我们将海洋贻贝波纹巴非蛤暴露于微聚苯乙烯与BDE - 47的混合物中21天，以测定贻贝的免疫防御、氧化应激和能量代谢情况。结果表明，暴露于单一微聚苯乙烯、单一BDE - 47或两者的贻贝的清除率（CR）均低于对照组。总体而言，与单一BDE - 47暴露相比，微聚苯乙烯与BDE - 47的组合显著提高了呼吸速率（RR）、酸性磷酸酶（ACP）和碱性磷酸酶（ALP）的活性、活性氧（ROS）的产生以及丙二醛（MDA）的浓度，但显著降低了乳酸脱氢酶（LDH）的活性和热休克蛋白（Hsp70和90）的相对表达。总体而言，联合应激对贻贝的防御性能和能量代谢有更不利的影响，微聚苯乙烯似乎加剧了BDE - 47的毒理学效应。由于未来微塑料污染可能会恶化，贻贝的健康在有机污染环境中可能会受到威胁，这最终会改变潮间带生态系统结构和功能的稳定性。
