Demirbaş Abdullah, Elmas Ömer Faruk
Department of Dermatology, Konya Numune Hospital, Konya, Turkey.
Department of Dermatology, Faculty of Medicine, Ahi Evran University, Kırşehir, Turkey.
J Cosmet Dermatol. 2021 Jan;20(1):316-320. doi: 10.1111/jocd.13481. Epub 2020 May 28.
Irritable bowel syndrome (IBS) is a functional gastrointestinal disease characterized by chronic abdominal pain and changes in bowel movements without underlying organic pathology. Many skin diseases have been reported to be more common in individuals with functional bowel diseases.
In this study, we aimed to investigate a possible relationship between acne vulgaris (AV) and IBS.
PATIENTS/METHODS: This prospective controlled study included patients with AV and healthy volunteers. All the subjects were evaluated in terms of the presence of IBS. The diagnosis of IBS was made based on the ROME IV diagnostic criteria. The clinical severity of AV was calculated using the global acne grading system (GAGS).
A total of 300 patients with acne vulgaris and 300 age and gender-matched healthy controls were included in the study. The majority of the patients were female (n = 175, 58.3%). The mean ages of the patients and controls were 20.22 ± 5.24 years and 20.49 ± 5.36 years, respectively. A total of 183 patients (61.0%) and 84 (28.0%) controls were diagnosed with IBS based on the Rome IV diagnostic criteria. The frequency of IBS was statistically significantly higher in the patient group than in the control group. (P = .001). There was also statistically significant relationship between the GAGS scores and IBS diagnosis (P = .001), abnormal stool form (P = .001), abdominal distention (P = .001), and feeling of incomplete evacuation (P = .001).
Our study showed that IBS is significantly more common in patients with AV than in healthy controls. Additionally, GAGS scores were higher in patients diagnosed with IBS. To the best of our knowledge, this is the first study focusing on the subject.
肠易激综合征（IBS）是一种功能性胃肠疾病，其特征为慢性腹痛和排便习惯改变，且无潜在的器质性病变。据报道，许多皮肤病在功能性肠病患者中更为常见。
在本研究中，我们旨在调查寻常痤疮（AV）与IBS之间可能存在的关系。
患者/方法：这项前瞻性对照研究纳入了寻常痤疮患者和健康志愿者。所有受试者均根据是否存在IBS进行评估。IBS的诊断基于罗马IV诊断标准。使用全球痤疮分级系统（GAGS）计算寻常痤疮的临床严重程度。
本研究共纳入300例寻常痤疮患者和300例年龄及性别匹配的健康对照。大多数患者为女性（n = 175，58.3%）。患者和对照的平均年龄分别为20.22±5.24岁和20.49±5.36岁。根据罗马IV诊断标准，共有183例患者（61.0%）和84例对照（28.0%）被诊断为IBS。患者组中IBS的发生率在统计学上显著高于对照组（P = .001）。GAGS评分与IBS诊断（P = .001）、异常粪便形态（P = .001）、腹胀（P = .001）和排便不尽感（P = .001）之间也存在统计学显著关系。
我们的研究表明，IBS在寻常痤疮患者中比在健康对照中明显更常见。此外，被诊断为IBS的患者GAGS评分更高。据我们所知，这是第一项关注该主题的研究。
