• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

预处理后的家用材料在过滤病原体方面与外科口罩具有相似的防护作用。

Pretreated household materials carry similar filtration protection against pathogens when compared with surgical masks.

机构信息

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Boston University, Boston, MA.

Division of Pulmonary and Critical Care Medicine, Department of Medicine, Boston University, Boston, MA.

出版信息

Am J Infect Control. 2020 Aug;48(8):883-889. doi: 10.1016/j.ajic.2020.05.024. Epub 2020 May 25.

DOI:10.1016/j.ajic.2020.05.024
PMID:32464294
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7255289/
Abstract

OBJECTIVE

The past 4 months, the emergence and spread of novel 2019 SARS-Cov-2 (COVID-19) has led to a global pandemic which is rapidly depleting supplies of personal protective equipment worldwide. There are currently over 1.6 million confirmed cases of COVID-19 worldwide which has resulted in more the 100,000 deaths. As these numbers grow daily, hospitals are being forced to reuse surgical masks in hopes of conserving their dwindling supply. Since COVID-19 will most likely have effects that last for many months, our nationwide shortage of masks poses a long term issue that must be addressed immediately.

METHODS

Based on a previous study by Quan et al., a salt-based soaking strategy has been reported to enhance the filtration ability of surgical masks. We propose a similar soaking process which uses materials widely available in anyone's household. We tested this method of pretreating a variety of materials with a salt-based solution by a droplet test using fluorescently stained nanoparticles similar in size to the COVID-19 virus.

RESULTS

In this study, we found that paper towels and surgical masks pretreated with the salt-based solution showed a noticeable increase in filtration of nanoparticles similar in size to the COVID-19 virus. We also show that the TWEEN20 used by Quan et al. is not a critical component for the solution, and using salt alone in solution still provides a dramatically increased level of protection.

CONCLUSIONS

We believe this method will allow for healthcare workers to create a disposable added layer of protection to their surgical masks, N95s, or homemade masks by using household available products. Adoption of this method may play an essential role in ensuring the safety of healthcare workers during the COVID-19 pandemic and any pandemics that may arise in the future.

摘要

目的

过去 4 个月,新型 2019 年 SARS-CoV-2(COVID-19)的出现和传播导致了一场全球大流行,全球个人防护设备的供应迅速枯竭。目前全球有超过 160 万例 COVID-19 确诊病例,导致超过 10 万人死亡。随着这些数字每天都在增加,医院被迫重复使用外科口罩,以希望节省日益减少的供应。由于 COVID-19 很可能会持续数月,因此我国口罩短缺是一个必须立即解决的长期问题。

方法

基于 Quan 等人的先前研究,已经报道了一种基于盐的浸泡策略来增强外科口罩的过滤能力。我们提出了一种类似的浸泡过程,该过程使用每个人家中都广泛可用的材料。我们通过使用与 COVID-19 病毒大小相似的荧光染色纳米颗粒进行液滴测试,测试了用基于盐的溶液预处理各种材料的这种方法。

结果

在这项研究中,我们发现用基于盐的溶液预处理的纸巾和外科口罩对大小相似的纳米颗粒的过滤能力明显提高。我们还表明,Quan 等人使用的 TWEEN20 不是溶液的关键成分,并且单独使用盐溶液仍能提供显著增强的保护水平。

结论

我们相信,这种方法将使医护人员能够通过使用家庭中可用的产品为外科口罩、N95 口罩或自制口罩创造一次性的附加保护层。在 COVID-19 大流行和未来可能出现的任何大流行期间,采用这种方法可能对确保医护人员的安全发挥重要作用。

相似文献

1
Pretreated household materials carry similar filtration protection against pathogens when compared with surgical masks.预处理后的家用材料在过滤病原体方面与外科口罩具有相似的防护作用。
Am J Infect Control. 2020 Aug;48(8):883-889. doi: 10.1016/j.ajic.2020.05.024. Epub 2020 May 25.
2
A laboratory-based study examining the properties of silk fabric to evaluate its potential as a protective barrier for personal protective equipment and as a functional material for face coverings during the COVID-19 pandemic.一项基于实验室的研究,旨在探究丝绸织物的特性,评估其在 COVID-19 大流行期间作为个人防护装备的防护屏障以及作为口罩功能材料的潜力。
PLoS One. 2020 Sep 18;15(9):e0239531. doi: 10.1371/journal.pone.0239531. eCollection 2020.
3
Global risk to the community and clinical setting: Flocking of fake masks and protective gears during the COVID-19 pandemic.对社区和临床环境的全球风险:新冠疫情期间假口罩和防护装备的大量涌现。
Am J Infect Control. 2020 Aug;48(8):964-965. doi: 10.1016/j.ajic.2020.05.008. Epub 2020 May 13.
4
Proposal for a EN 149 acceptable reprocessing method for FFP2 respirators in times of severe shortage.严重短缺时期,FFP2 呼吸器的 EN 149 可接受再处理方法提案。
Antimicrob Resist Infect Control. 2020 Jun 17;9(1):88. doi: 10.1186/s13756-020-00744-3.
5
Evaluation of Protection Level, Respiratory Safety, and Practical Aspects of Commercially Available Snorkel Masks as Personal Protection Devices Against Aerosolized Contaminants and SARS-CoV2.评估商业性通气管面罩作为个人防护装置防止气溶胶污染物和 SARS-CoV2 的防护水平、呼吸安全性和实际方面。
Int J Environ Res Public Health. 2020 Jun 19;17(12):4347. doi: 10.3390/ijerph17124347.
6
Medical masks and Respirators for the Protection of Healthcare Workers from SARS-CoV-2 and other viruses.医用口罩和呼吸器用于保护医护人员免受 SARS-CoV-2 和其他病毒的侵害。
Pulmonology. 2020 Jul-Aug;26(4):204-212. doi: 10.1016/j.pulmoe.2020.04.009. Epub 2020 Apr 27.
7
Potential Makeshift Solution to Coronavirus Disease 2019-Related N95 Mask Shortage.针对2019冠状病毒病相关N95口罩短缺的潜在临时解决方案。
A A Pract. 2020 Jul;14(9):e01280. doi: 10.1213/XAA.0000000000001280.
8
Filtration Efficiencies of Nanoscale Aerosol by Cloth Mask Materials Used to Slow the Spread of SARS-CoV-2.织物口罩材料对 SARS-CoV-2 传播的减缓作用下的纳米气溶胶过滤效率。
ACS Nano. 2020 Jul 28;14(7):9188-9200. doi: 10.1021/acsnano.0c05025. Epub 2020 Jul 7.
9
[Respiratory and Facial Protection: Current Perspectives in the Context of the COVID-19 Pandemic].[呼吸道与面部防护:COVID-19大流行背景下的当前观点]
Acta Med Port. 2020 Sep 1;33(9):583-592. doi: 10.20344/amp.14108. Epub 2020 Jun 19.
10
A cloth mask for under-resourced healthcare settings in the COVID19 pandemic.COVID19 大流行期间资源匮乏的医疗环境中使用的布制口罩。
Ir J Med Sci. 2020 Nov;189(4):1155-1157. doi: 10.1007/s11845-020-02241-3. Epub 2020 May 12.

引用本文的文献

1
Bacterial Outer Membrane Vesicles Promote Lung Inflammatory Responses and Macrophage Activation via Multi-Signaling Pathways.细菌外膜囊泡通过多信号通路促进肺部炎症反应和巨噬细胞活化。
Biomedicines. 2023 Feb 15;11(2):568. doi: 10.3390/biomedicines11020568.
2
Conservation Practices for Personal Protective Equipment: A Systematic Review with Focus on Lower-Income Countries.个人防护设备的保护措施:一项侧重于低收入国家的系统评价。
Int J Environ Res Public Health. 2023 Jan 31;20(3):2575. doi: 10.3390/ijerph20032575.

本文引用的文献

1
Facial protection for healthcare workers during pandemics: a scoping review.大流行期间医护人员的面部防护:范围综述。
BMJ Glob Health. 2020 May;5(5). doi: 10.1136/bmjgh-2020-002553.
2
Identification of Coronavirus Isolated from a Patient in Korea with COVID-19.从韩国一名新冠肺炎患者身上分离出的冠状病毒的鉴定。
Osong Public Health Res Perspect. 2020 Feb;11(1):3-7. doi: 10.24171/j.phrp.2020.11.1.02.
3
Outer Membrane Vesicles Derived From Regulate Neutrophil Migration by Induction of Endothelial IL-8.源自[具体内容未给出]的外膜囊泡通过诱导内皮细胞白细胞介素-8来调节中性粒细胞迁移。
Front Microbiol. 2018 Oct 11;9:2268. doi: 10.3389/fmicb.2018.02268. eCollection 2018.
4
Universal and reusable virus deactivation system for respiratory protection.通用且可重复使用的呼吸道防护病毒灭活系统。
Sci Rep. 2017 Jan 4;7:39956. doi: 10.1038/srep39956.
5
Outer-membrane vesicles from Gram-negative bacteria: biogenesis and functions.革兰氏阴性菌的外膜囊泡:生物发生与功能
Nat Rev Microbiol. 2015 Oct;13(10):605-19. doi: 10.1038/nrmicro3525.