从海洋弧菌生物血清群1875中分离出的O抗原性脂多糖，与O1霍乱弧菌具有共同的抗原因子。

O-antigenic lipopolysaccharides isolated from a marine Vibrio, bio-serogroup 1875, possessing an antigenic factor in common with O1 Vibrio cholerae.

作者信息

Haishima Y, Kondo S, Hisatsune K

机构信息

Department of Microbiology, School of Pharmaceutical Sciences, Josai University, Saitama, Japan.

出版信息

J Gen Microbiol. 1988 Jul;134(7):1827-33. doi: 10.1099/00221287-134-7-1827.

DOI:10.1099/00221287-134-7-1827

PMID:3246586

Abstract

The chemical and serological characteristics of lipopolysaccharides (LPS) isolated from Vibrio bio-serogroup 1875 were compared with those of O1 Vibrio cholerae LPS. Vibrio bio-serogroup 1875 LPS contained all the component sugars which were found in O1 V. cholerae LPS, i.e. glucose, L-glycero-D-manno-heptose, fructose, glucosamine, perosamine and quinovosamine, though the amount of perosamine, a characteristic component of O1 V. cholerae LPS, was very low compared with that of O1 V. cholerae LPS. Their LPS additionally contained mannose and two unidentified neutral sugars which are not regular constituents of O1 V. cholerae LPS. Definite serological cross-reactivity in the passive haemolysis test between LPS from Vibrio bio-serogroup 1875 and LPS from O1 V. cholerae was demonstrated.

摘要

将从生物血清群1875弧菌分离出的脂多糖（LPS）的化学和血清学特征与霍乱弧菌O1 LPS的特征进行了比较。生物血清群1875弧菌LPS含有在霍乱弧菌O1 LPS中发现的所有组成糖，即葡萄糖、L-甘油-D-甘露庚糖、果糖、葡糖胺、鼠李糖胺和奎诺糖胺，不过与霍乱弧菌O1 LPS相比，鼠李糖胺（霍乱弧菌O1 LPS的特征成分）的含量非常低。它们的LPS还含有甘露糖和两种未鉴定的中性糖，这些不是霍乱弧菌O1 LPS的常规成分。在被动溶血试验中，证明了生物血清群1875弧菌LPS与霍乱弧菌O1 LPS之间存在明确的血清学交叉反应。