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突尼斯链霉菌 DSM 105760 的基因组草图序列

Draft genome sequence of Streptomyces tunisialbus DSM 105760.

机构信息

Laboratory of Bioactive Substances, Biotechnology Center of Borj-Cedria (CBBC), BP-901, 2050, Hammam-Lif, Tunisia.

Center for Biotechnology (CeBiTec), Bielefeld University, 33501, Bielefeld, Germany.

出版信息

Arch Microbiol. 2020 Sep;202(7):2013-2017. doi: 10.1007/s00203-020-01913-z. Epub 2020 May 30.

DOI:10.1007/s00203-020-01913-z
PMID:32474644
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7385001/
Abstract

Streptomyces strains are well known as promising source of bioactive secondary metabolites, important in ecology, biotechnology and medicine. In this study, we present the draft genome of the new type strain Streptomyces tunisialbus DSM 105760 (= JCM 32165), a rhizospheric bacterium with antimicrobial activity. The genome is 6,880,753 bp in size (average GC content, 71.85%) and encodes 5802 protein-coding genes. Preliminary analysis with antiSMASH 5.1.2. reveals 34 predicted gene clusters for the synthesis of potential secondary metabolites, which was compared with those of Streptomyces varsoviensis NRRL ISP-5346.

摘要

链霉菌菌株是生物活性次级代谢产物的有前途的来源，在生态学、生物技术和医学中具有重要作用。在这项研究中，我们介绍了新型链霉菌突尼斯亚种 DSM 105760（=JCM 32165）的基因组草图，该菌株是一种具有抗菌活性的根际细菌。该基因组大小为 6880753bp（平均 GC 含量为 71.85%），编码 5802 个蛋白编码基因。使用 antiSMASH 5.1.2 进行初步分析，揭示了 34 个预测的用于合成潜在次级代谢产物的基因簇，与链霉菌沃罗涅日亚种 NRRL ISP-5346 的基因簇进行了比较。

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