Faculty of Medical Sciences, University of Guayaquil, Guayaquil, Ecuador.
Physiology and Respiratory-Center Briones-Claudett, Guayaquil, Ecuador.
Am J Case Rep. 2020 Jun 1;21:e923349. doi: 10.12659/AJCR.923349.
BACKGROUND Tetanus is a potentially fatal infectious disease which, during its evolution, creates multiple complications, usually requiring intensive management and care. CASE REPORT We present a clinical case of a 59-year-old male patient with generalized tetanus admitted to the intensive care unit. Flexible bronchoscopy revealed contraction of the bronchial demonstrating that tetany existed at the respiratory level, which rarely becomes evident. The clinical manifestations included trismus, facial paralysis, neck stiffness, and compromised respiratory function. The patient presented a state of respiratory failure that required invasive mechanical ventilation which was evaluated by bronchoscopy and that showed spasms of the bronchial musculature. The patient presented generalized tetanus in which the bronchial affectation was evaluated by bronchoscopy in the intensive care unit. In developed countries, the anti-tetanus toxoid vaccine has ostensibly decreased its incidence, while it is endemic in developing countries, and although there are measures such as vaccination that try to reduce its incidence, in Ecuador there is an increase in incidences. In this patient case, contraction of the bronchial rings was observed, demonstrating that tetany existed at the respiratory level, which rarely becomes evident. CONCLUSIONS Although muscular contractions are widespread, this clinical case evidences bronchial spams reported and visualized by bronchoscopy.
破伤风是一种潜在致命的传染病,在其发展过程中会产生多种并发症,通常需要强化管理和护理。
我们报告了一例 59 岁男性全身破伤风患者,收入重症监护病房。软性支气管镜检查显示支气管收缩,表明存在呼吸性搐搦,这很少变得明显。临床表现包括牙关紧闭、面瘫、颈部僵硬和呼吸功能受损。患者出现呼吸衰竭,需要进行有创机械通气,通过支气管镜进行评估,显示支气管肌肉痉挛。患者出现全身破伤风,在重症监护病房通过支气管镜评估支气管受累情况。在发达国家,破伤风类毒素疫苗的使用明显降低了其发病率,而在发展中国家则流行,尽管有疫苗接种等措施试图降低其发病率,但在厄瓜多尔,发病率却有所上升。在本例患者中,观察到支气管环收缩,表明存在呼吸性搐搦,这很少变得明显。
尽管肌肉收缩广泛存在,但本临床病例报告并通过支气管镜观察到支气管痉挛。