Cheng Yibin, Shang Dantong, Luo Majing, Huang Chunhua, Lai Fengling, Wang Xin, Xu Xu, Ying Ruhong, Wang Lingling, Zhao Yu, Zhang Li, Long Manyuan, Cheng Hanhua, Zhou Rongjia
1Hubei Key Laboratory of Cell Homeostasis, College of Life Sciences, Wuhan University, Wuhan, 430072 People's Republic of China.
2Department of Ecology and Evolution, University of Chicago, Chicago, 60637 USA.
Cell Biosci. 2020 May 20;10:67. doi: 10.1186/s13578-020-00432-0. eCollection 2020.
Teleost fishes account for over half of extant vertebrate species. A core question in biology is how genomic changes drive phenotypic diversity that relates to the origin of teleost fishes.
Here, we used comparative genomic analyses with chromosome assemblies of diverse lineages of vertebrates and reconstructed an ancestral vertebrate genome, which revealed phylogenomic trajectories in vertebrates. We found that the whole-genome-wide chromosome fission/fusions took place in the lineage after the 3-round whole-genome duplication. Four times of genomic fission/fusions events resulted in the whole genome-wide chromosome fusions in the genomic history of the lineage. In addition, abundant recently evolved new genes for reproduction emerged in the after separated from medaka. Notably, we described evolutionary trajectories of conserved blocks related to sex determination genes in teleosts.
These data pave the way for a better understanding of genomic evolution in extant teleosts.
硬骨鱼占现存脊椎动物物种的一半以上。生物学中的一个核心问题是基因组变化如何驱动与硬骨鱼起源相关的表型多样性。
在这里，我们对不同脊椎动物谱系的染色体组装进行了比较基因组分析，并重建了一个祖先脊椎动物基因组，揭示了脊椎动物的系统发育轨迹。我们发现，全基因组范围内的染色体裂变/融合发生在三轮全基因组复制之后的谱系中。四次基因组裂变/融合事件导致了该谱系基因组历史上全基因组范围内的染色体融合。此外，在与青鳉分离后，该谱系中出现了大量最近进化出的生殖新基因。值得注意的是，我们描述了硬骨鱼中与性别决定基因相关的保守区域的进化轨迹。
这些数据为更好地理解现存硬骨鱼的基因组进化铺平了道路。
