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用于确证医学关系的文本片段:一种使用知识图谱和嵌入的无监督方法。

Text Snippets to Corroborate Medical Relations: An Unsupervised Approach using a Knowledge Graph and Embeddings.

作者信息

Kamdar Maulik R, Stanley Craig E, Carroll Michael, Wogulis Linda, Dowling William, Deus Helena F, Samarasinghe Mevan

机构信息

Elsevier, Health and Commercial Markets, Philadelphia, PA.

出版信息

AMIA Jt Summits Transl Sci Proc. 2020 May 30;2020:288-297. eCollection 2020.

PMID:32477648
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7233036/
Abstract

Knowledge graphs have been shown to significantly improve search results. Usually populated by subject matter experts, relations therein need to keep up to date with medical literature in order for search to remain relevant. Dynamically identifying text snippets in literature that confirm or deny knowledge graph triples is increasingly becoming the differentiator between trusted and untrusted medical decision support systems. This work describes our approach to mapping triples to medical text. A medical knowledge graph is used as a source of triples that are used to find matching sentences in reference text. Our unsupervised approach uses phrase embeddings and cosine similarity measures, and boosts candidate text snippets when certain key concepts exist. Using this approach, we can accurately map semantic relations within the medical knowledge graph to text snippets with a precision of 61.4% and recall of 86.3%. This method will be used to develop a novel application in the future to retrieve medical relations and corroborating snippets from medical text given a user query.

摘要

知识图谱已被证明能显著改善搜索结果。通常由主题专家填充,其中的关系需要与医学文献保持同步更新,以便搜索结果仍具相关性。动态识别文献中确认或否定知识图谱三元组的文本片段,正日益成为可信和不可信医学决策支持系统之间的区别所在。这项工作描述了我们将三元组映射到医学文本的方法。医学知识图谱被用作三元组的来源,用于在参考文献中查找匹配的句子。我们的无监督方法使用短语嵌入和余弦相似度度量,并在存在某些关键概念时增强候选文本片段。使用这种方法,我们可以将医学知识图谱中的语义关系准确地映射到文本片段,精确率为61.4%,召回率为86.3%。该方法未来将用于开发一种新颖的应用程序,以便在给定用户查询时从医学文本中检索医学关系和确证性片段。

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本文引用的文献

1
Enabling Web-scale data integration in biomedicine through Linked Open Data.通过关联开放数据实现生物医学领域的网络规模数据集成。
NPJ Digit Med. 2019 Sep 10;2:90. doi: 10.1038/s41746-019-0162-5. eCollection 2019.
2
Modeling polypharmacy side effects with graph convolutional networks.基于图卷积网络的药物滥用副作用建模。
Bioinformatics. 2018 Jul 1;34(13):i457-i466. doi: 10.1093/bioinformatics/bty294.
3
A global network of biomedical relationships derived from text.从文本中提取的生物医学关系的全球网络。
Bioinformatics. 2018 Aug 1;34(15):2614-2624. doi: 10.1093/bioinformatics/bty114.
4
PhLeGrA: Graph Analytics in Pharmacology over the Web of Life Sciences Linked Open Data.PhLeGrA:生命科学链接开放数据网络上的药理学图形分析
Proc Int World Wide Web Conf. 2017 Apr;2017:321-329. doi: 10.1145/3038912.3052692.
5
Indexed Pain Journals.索引疼痛期刊。
J Pain Palliat Care Pharmacother. 2008;22(1):45-46. doi: 10.1080/15360280801989377.
6
Pharmacovigilance from social media: mining adverse drug reaction mentions using sequence labeling with word embedding cluster features.社交媒体中的药物警戒:使用带有词嵌入聚类特征的序列标注挖掘药物不良反应提及信息。
J Am Med Inform Assoc. 2015 May;22(3):671-81. doi: 10.1093/jamia/ocu041. Epub 2015 Mar 9.
7
Clinical questions raised by clinicians at the point of care: a systematic review.临床医生在护理点提出的临床问题:系统评价。
JAMA Intern Med. 2014 May;174(5):710-8. doi: 10.1001/jamainternmed.2014.368.
8
ReVeaLD: a user-driven domain-specific interactive search platform for biomedical research.ReVeaLD:一个用户驱动的生物医学研究领域特定交互式搜索平台。
J Biomed Inform. 2014 Feb;47:112-30. doi: 10.1016/j.jbi.2013.10.001. Epub 2013 Oct 14.
9
Barriers and decisions when answering clinical questions at the point of care: a grounded theory study.在护理点回答临床问题时的障碍和决策:扎根理论研究。
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10
Challenges and opportunities facing medical education.医学教育面临的挑战与机遇。
Trans Am Clin Climatol Assoc. 2011;122:48-58.