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甲病对生活质量的影响:一项基于医院的横断面研究。

The Impact of Onychopathies on Quality of Life: A Hospital-based, Cross-sectional Study.

作者信息

Tabassum Hera, Adil Mohammad, Amin Syed S, Mohtashim Mohd, Bansal Roopal, Agrawal Divya

机构信息

Department of Dermatology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.

出版信息

Indian Dermatol Online J. 2020 Mar 9;11(2):187-194. doi: 10.4103/idoj.IDOJ_272_19. eCollection 2020 Mar-Apr.

DOI:10.4103/idoj.IDOJ_272_19
PMID:32477977
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7247629/
Abstract

BACKGROUND

Onychopathies or nail disorders are associated with social stigma and causes limitation of daily activities by hampering the function of both fingers and toes.

AIM

To evaluate the impact of onychopathies on quality of life (QoL) and compare the severity of impact on QoL in various nail disorders.

MATERIALS AND METHODS

A hospital-based cross-sectional study consisting of 540 patients with onychopathies was conducted in the dermatology outpatient department. Patients were requested to complete a nail-specific QoL questionnaire consisting of 24 and 16 questions, respectively, for fingernails (group F) and toenails (group T) with five possible responses to each question. A score of 1-5 was given to each response. Statistical analysis was done to compare the impact of QoL on the different types of onychopathies.

RESULTS

We found that onychopathies have a significant impact on QoL. QoL was significantly more affected when multiple nails were involved ( = 0.020 for group F and = 0.001 for group T). QoL impact was statistically more significant in women ( = 0.038 for group F and < 0.001 for group T) and in younger people aged <20 years in group F and 20-39 years in group T ( < 0.001 for both groups F and T). Patients with onychomycosis, structural nail defects, and psoriasis had a more significant impact than other diseases ( < 0.001 for both groups F and T).

CONCLUSION

Onychopathies have a significant adverse effect on QoL because of their serious physical, psychological and social impact. Hence, clinicians should treat the nail disorders with utmost seriousness.

摘要

背景

甲病或指甲疾病与社会污名相关,并通过妨碍手指和脚趾的功能导致日常活动受限。

目的

评估甲病对生活质量(QoL)的影响,并比较各种指甲疾病对生活质量影响的严重程度。

材料与方法

在皮肤科门诊进行了一项基于医院的横断面研究,纳入了540例甲病患者。要求患者完成一份指甲特异性生活质量问卷,该问卷分别针对手指甲(F组)和脚趾甲(T组)包含24个和16个问题,每个问题有五种可能的回答。每个回答给予1-5分。进行统计分析以比较生活质量对不同类型甲病的影响。

结果

我们发现甲病对生活质量有显著影响。当多个指甲受累时,生活质量受影响更显著(F组P = 0.020,T组P = 0.001)。生活质量影响在女性中在统计学上更显著(F组P = 0.038,T组P < 0.001),在F组年龄<20岁和T组年龄20-39岁的年轻人中也是如此(F组和T组P均< 0.001)。甲癣、结构性指甲缺陷和银屑病患者比其他疾病有更显著的影响(F组和T组P均< 0.001)。

结论

由于甲病严重的身体、心理和社会影响,其对生活质量有显著的不利影响。因此,临床医生应极其严肃地对待指甲疾病。

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本文引用的文献

1
Onychomycosis: A study of self-recognition by patients and quality of life.甲癣:一项关于患者自我认知及生活质量的研究。
Indian J Dermatol Venereol Leprol. 2015 May-Jun;81(3):270-4. doi: 10.4103/0378-6323.154796.
2
The impact of nail disorders on quality of life.指甲疾病对生活质量的影响。
Eur J Dermatol. 2013 May-Jun;23(3):366-71. doi: 10.1684/ejd.2013.2048.
3
[Non traumatic lesions of the foot, calluses and nails: socioeconomic impact of an unexplored issue].[足部非创伤性病变、胼胝和指甲:一个未被探索问题的社会经济影响]
Rev Med Suisse. 2011 Nov 2;7(315):2148-52.
4
Health-related quality of life in patients with nail disorders.患者指甲疾病相关的生活质量。
Am J Clin Dermatol. 2011 Oct 1;12(5):313-20. doi: 10.2165/11592120-000000000-00000.
5
Nail psoriasis in Germany: epidemiology and burden of disease.德国甲银屑病的流行病学和疾病负担。
Br J Dermatol. 2010 Sep;163(3):580-5. doi: 10.1111/j.1365-2133.2010.09831.x. Epub 2010 Apr 28.
6
Development and validation of nail psoriasis quality of life scale (NPQ10).指甲银屑病生活质量量表(NPQ10)的制定与验证。
J Eur Acad Dermatol Venereol. 2010 Jan;24(1):22-7. doi: 10.1111/j.1468-3083.2009.03344.x.
7
Treatment of nail psoriasis with adalimumab: an open label unblinded study.阿达木单抗治疗甲银屑病:一项开放性、非盲研究。
J Eur Acad Dermatol Venereol. 2010 May;24(5):530-4. doi: 10.1111/j.1468-3083.2009.03453.x. Epub 2009 Oct 6.
8
Psoriatic nail disease: quality of life and treatment.银屑病甲病:生活质量与治疗。
J Cutan Med Surg. 2009 Sep-Oct;13 Suppl 2:S102-6. doi: 10.2310/7750.2009.00027.
9
Stigmatisation in onychomycosis patients: a population-based study.甲真菌病患者的污名化:一项基于人群的研究。
Mycoses. 2009 Jul;52(4):343-9. doi: 10.1111/j.1439-0507.2008.01618.x. Epub 2008 Sep 12.
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NailQoL: a quality-of-life instrument for onychomycosis.甲真菌病生活质量量表:一种用于甲真菌病的生活质量评估工具。
Int J Dermatol. 2007 Dec;46(12):1279-86. doi: 10.1111/j.1365-4632.2007.03362.x.