Marchandot Benjamin, Sattler Laurent, Jesel Laurence, Matsushita Kensuke, Schini-Kerth Valerie, Grunebaum Lelia, Morel Olivier
Université de Strasbourg, Pôle d'Activité Médico-Chirurgicale Cardio-Vasculaire, Nouvel Hôpital Civil, Centre Hospitalier Universitaire, 67000 Strasbourg, France.
Université de Strasbourg, Pôle de Biologie, Département d'Hémostase, Centre Hospitalier Universitaire, 67000 Strasbourg, France.
J Clin Med. 2020 May 31;9(6):1651. doi: 10.3390/jcm9061651.
The coronavirus disease 2019 (COVID-19) pandemic has impacted healthcare communities across the globe on an unprecedented scale. Patients have had diverse clinical outcomes, but those developing COVID-19-related coagulopathy have shown a disproportionately worse outcome. This narrative review summarizes current evidence regarding the epidemiology, clinical features, known and presumed pathophysiology-based models, and treatment guidance regarding COVID-19 coagulopathy.
2019年冠状病毒病(COVID-19)大流行以前所未有的规模影响了全球医疗界。患者有各种各样的临床结果,但那些出现与COVID-19相关凝血病的患者表现出了格外糟糕的结果。这篇叙述性综述总结了关于COVID-19凝血病的流行病学、临床特征、基于已知和推测病理生理学的模型以及治疗指南的当前证据。