Department of Psychology, Michigan State University, East Lansing, Michigan, USA.
Int J Eat Disord. 2020 Sep;53(9):1569-1578. doi: 10.1002/eat.23302. Epub 2020 Jun 3.
While studies in humans suggest a role for psychosocial factors as well as biological and genetic processes in the development of eating disorders, the specific etiologic mechanisms remain largely unknown. In this virtual issue, we present a collection of 14 archived articles from the International Journal of Eating Disorders to highlight the utility of animal studies of eating disorders to advance our understanding of eating disorder etiology. Selected articles establish animal studies as valid tools to study disordered eating behavior, offer insight into potential neurobiological mechanisms, and highlight novel targets for future pharmacological treatments. Clinical implications of each article's findings are included to demonstrate the translational value of animal studies for the eating disorders field. We hope that the exciting concepts and findings in this issue inspire future animal studies of eating disorders.
虽然人类研究表明，心理社会因素以及生物和遗传过程在饮食失调的发展中起作用，但具体的病因机制在很大程度上仍然未知。在本期虚拟特刊中，我们从《国际饮食失调杂志》中精选了 14 篇存档文章，重点介绍了饮食失调动物研究在增进我们对饮食失调病因理解方面的作用。选定的文章将动物研究确立为研究饮食失调行为的有效工具，提供了对潜在神经生物学机制的深入了解，并突出了未来药物治疗的新靶点。每篇文章的研究结果都包含了临床意义，以证明动物研究对饮食失调领域的转化价值。我们希望本期特刊中的这些令人兴奋的概念和发现能够激发未来对饮食失调的动物研究。
