Walsh B T, Devlin M J
New York State Psychiatric Institute and the College of Physicians & Surgeons, Columbia University, 722 West 168th Street, New York, NY 10032, USA.
Science. 1998 May 29;280(5368):1387-90. doi: 10.1126/science.280.5368.1387.
Recent research on Anorexia Nervosa and Bulimia Nervosa has yielded an increasingly detailed understanding of the range of biological and psychological abnormalities associated with these eating disorders. Inherited vulnerabilities, cultural pressures, and adverse individual and family experiences all appear to contribute to the onset of extreme dieting, binge eating, and purging. Once initiated, these behaviors give rise to multiple physiological disturbances, some of which may serve to perpetuate the illness. Although there have been substantial advances in the management of Bulimia Nervosa, the goal of offering effective treatment to all individuals with eating disorders remains elusive. This article reviews current thinking on the etiology and treatment of the two major eating disorders and a related syndrome, Binge Eating Disorder.
近期对神经性厌食症和神经性贪食症的研究，已使人们对与这些饮食失调相关的一系列生物和心理异常有了越来越详尽的认识。遗传易感性、文化压力以及不良的个人和家庭经历似乎都促使了极端节食、暴饮暴食和催吐行为的发生。一旦这些行为开始，就会引发多种生理紊乱，其中一些可能会使病情持续下去。尽管在神经性贪食症的治疗方面已取得了重大进展，但为所有饮食失调患者提供有效治疗的目标仍难以实现。本文综述了关于这两种主要饮食失调症以及一种相关综合征——暴饮暴食症的病因和治疗的当前观点。
