Large Animal Medicine and Surgery Department, School of Veterinary Medicine, St. George's University, St. George's, Grenada.
College of Veterinary Medicine, North Carolina State University, Raleigh, NC, USA.
J Vet Pharmacol Ther. 2020 Sep;43(5):421-428. doi: 10.1111/jvp.12874. Epub 2020 Jun 3.
Ectoparasites infestations are a growing concern to horse owners and equine veterinarians alike. Ectoparasites cause significant health and welfare issues and can potentially can serve as vectors for a variety of pathogens. The prevalence of ectoparasites increases around the world, and especially in horses information on the successful prevention and treatment of ectoparasite infestations in scarce and in many instances anecdotal. This poses a challenge to the equine veterinarian and off-label use of drugs can lead to detrimental effects in horses. In this review we describe the current available evidence for the prevention and treatment of ectoparasite infestations in horses. Only a very limited number of products is approved for the use in horses and fortunately many of the other products that are used in an off-label manner appear to be safe in horses. Future research in this area should aim at providing PK/PD modelling data to assure appropriate and safe dose regimen to prevent and treat ectoparasite infestations in horses.
体外寄生虫感染是马主和兽医共同关注的问题。体外寄生虫会导致严重的健康和福利问题，并且可能作为各种病原体的传播媒介。体外寄生虫的流行率在全球范围内增加，特别是在马匹中，有关成功预防和治疗体外寄生虫感染的信息稀缺，在许多情况下只是传闻。这对兽医来说是一个挑战，并且药物的标签外使用可能会对马造成有害影响。在这篇综述中，我们描述了目前可用于预防和治疗马体外寄生虫感染的证据。只有极少数产品被批准用于马，幸运的是，许多以标签外方式使用的其他产品在马中似乎是安全的。该领域的未来研究应旨在提供 PK/PD 建模数据，以确保适当和安全的剂量方案，以预防和治疗马的体外寄生虫感染。
