新型冠状病毒2型脓毒症中的血栓炎症反应。
Thromboinflammatory response in SARS-CoV-2 sepsis.
作者信息
Maiese Aniello, Passaro Giovanna, Matteis Alessandra DE, Fazio Valentina, Raffaele La Russa, Paolo Marco Di
机构信息
Department of Surgical Pathology, Medical, Molecular and Critical Area, Institute of Legal Medicine, University of Pisa, Pisa, Italy.
Gemelli IRCCS Research Hospital, Fondazione Policlinico Universitario A. Rome, Italy.
出版信息
Med Leg J. 2020 Jul;88(2):78-80. doi: 10.1177/0025817220926915. Epub 2020 Jun 3.
Viral sepsis is rare, and its real incidence is not known. SARS-CoV-2 infection causes the release of a significant amount of pro-inflammatory cytokines that aggravates interstitial pneumonia and evolves in viral sepsis with prominent hypercoagulability. We believe it is useful and advisable to establish early immunomodulator therapy and the prophylaxis anticoagulant therapy should be rethought.
病毒性脓毒症较为罕见，其实际发病率尚不清楚。新型冠状病毒感染会导致大量促炎细胞因子释放，加重间质性肺炎，并演变为具有显著高凝性的病毒性脓毒症。我们认为早期建立免疫调节治疗是有用且可取的，同时应重新考虑预防性抗凝治疗。
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