Centro de Investigação em Actividade Física, Saúde e Lazer, Faculdade de Desporto, Universidade do Porto, Porto, Portugal.
Faculdade de Medicina da Universidade do Porto (FMUP), Unidade de Investigação Cardiovascular (UniC),5 Porto – Portugal
Arq Bras Cardiol. 2020 Apr;114(4):701-707. doi: 10.36660/abc.20190080. Epub 2020 May 29.
Background Physical fitness is an important determinant of quality of life (QoL) in heart failure with preserved ejection fraction (HFpEF) patients. However, how the different physical fitness components correlate with the specific dimensions of QoL in HFpEF patients remains unknown. Objective To evaluate the association between different physical fitness components and QoL dimensions in HFpEF patients, and, assess which physical fitness components were independently associated to QoL. Methods Patients with HFpEF were assessed for physical fitness [dynamic balance and mobility (8-foot-up-and go test), upper body strength (handgrip), cardiorespiratory fitness (CRF) (6-minute-walking test) and body composition (body mass index)] and for QoL (Minnesota Living With Heart Failure Questionnaire). Partial correlation was used to verify the association between physical fitness components and QoL dimensions. The determination of independent predictors in QoL dimensions was assessed through stepwise multivariate linear regression analysis. Statistical significance was set at p<0.05. Results Both CRF and dynamic balance and mobility are significantly associated with the total score and physical dimensions of QoL (p<0.05), but only dynamic balance and mobility were concomitantly associated with the emotional dimension (r=0.597; p=0.004). Dynamic balance and mobility were independently associated with total score (β=0.651; r2=0.424; p=0.001), physical (β=0.570; r2=0.324; p=0.04) and emotional (β=0.611; r2=0.373 p=0.002) dimensions of QoL. Conclusion Our data suggests that dynamic balance and mobility better assess QoL than CRF, which is commonly measured in clinical practice. Whether interventions specifically targeting dynamic balance and mobility have different impacts on QoL remains unknown. (Arq Bras Cardiol. 2020; 114(4):701-707).
身体适能是射血分数保留型心力衰竭（HFpEF）患者生活质量（QoL）的重要决定因素。然而，HFpEF 患者不同身体适能成分与 QoL 特定维度的相关性仍不清楚。目的：评估 HFpEF 患者不同身体适能成分与 QoL 维度的相关性，并评估哪些身体适能成分与 QoL 独立相关。方法：对 HFpEF 患者进行身体适能[动态平衡和移动性（8 英尺向上和走测试）、上肢力量（握力）、心肺适能（6 分钟步行测试）和身体成分（体重指数）]和 QoL（明尼苏达州心力衰竭生活质量问卷）评估。使用偏相关来验证身体适能成分与 QoL 维度之间的相关性。通过逐步多元线性回归分析评估 QoL 维度中独立预测因子的确定。统计学意义设为 p<0.05。结果：心肺适能和动态平衡与移动性均与 QoL 的总分和身体维度显著相关（p<0.05），但只有动态平衡与移动性与情绪维度同时相关（r=0.597；p=0.004）。动态平衡与移动性与总分（β=0.651；r2=0.424；p=0.001）、身体（β=0.570；r2=0.324；p=0.04）和情绪（β=0.611；r2=0.373 p=0.002）维度的 QoL 独立相关。结论：我们的数据表明，动态平衡与移动性比心肺适能更能评估 QoL，后者在临床实践中通常被测量。针对动态平衡与移动性的干预措施是否对 QoL 有不同的影响仍不清楚。（Arq Bras Cardiol. 2020; 114(4):701-707）。
