Serous Pancreatic Neoplasms

Pancreatic serous cystadenomas are mostly benign and considered among the common primary pancreatic cystic neoplasms (PCNs), representing one-third (see Serous Cystadenoma, CT). Patients are usually asymptomatic. Other types of PCNs include mucinous cystic neoplasm, intraductal papillary Mucinous neoplasm, cystic neuroendocrine neoplasm, solid-pseudopapillary neoplasm, acinar-cell cystic neoplasm, and ductal adenocarcinoma with cystic degeneration. Due to the increased use and advances in cross-sectional imaging of the abdomen, the detection of these lesions has improved, especially in asymptomatic patients. This topic discusses the pathophysiology, clinical presentation, diagnosis, and treatment of pancreatic serous cystadenoma.