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纳米银氟化物预处理对抑制牙齿修复界面继发龋的体外比较评价

An In-Vitro Comparative Evaluation of Pre-treatment With Nano-Silver Fluoride on Inhibiting Secondary Caries at Tooth Restoration Interface.

作者信息

Nanda Konica J, Naik Shilpa

机构信息

Department of Pedodontics and Preventive Dentistry, D.Y. Patil University School of Dentistry, Mumbai, IND.

出版信息

Cureus. 2020 May 2;12(5):e7934. doi: 10.7759/cureus.7934.

Abstract

Introduction and aim Dental caries is the global burden worldwide and has a negative effect on the quality of life. Restorative materials in pediatric dentistry have shown satisfactory properties; however, the highest failures are still reported due to the occurrence of secondary caries. The article aims to assess the effectiveness of pre-treatment with nano-silver fluoride (NSF) in inhibiting secondary caries at the tooth restoration interface. Materials and methods Forty tooth specimens were prepared from 20 newly extracted human premolar teeth by sectioning the tooth mesiodistally. Class V cavities were prepared on each specimen at enamel dentin junction. Specimens were randomly distributed into four groups (n=10): 1) glass ionomer cement (GIC) restoration, 2) composite restoration 3) NSF pre-treatment + GIC restoration, 4) NSF pre-treatment + composite restoration. After sterilization, specimens were subjected to artificial caries formation by pH cycling method for 14 days. Specimens were sectioned and mounted to evaluate the demineralization by using the Vickers microhardness test. Outer lesion depth was measured at the tooth restoration interface on digital radiographs. Data was analyzed using Student unpaired t-test, one-way ANOVA, and Tukey honestly significant difference (HSD) post hoc test. Results The mean microhardness value of pre-treated GIC and composite group with NSF was more than the non-treated NSF group, with a significant difference at the enamel, indicating lesser demineralization. Outer lesion depth was lesser in the pre-treated group showing better tooth restoration integrity with a statistically significant difference between the groups. Conclusion Pre-treatment with NSF is beneficial in increasing the resistance of GIC and composite resin restoration to secondary caries formation.

摘要

引言与目的

龋齿是全球范围内的负担,对生活质量有负面影响。儿童牙科中的修复材料已显示出令人满意的性能;然而,由于继发龋的发生,仍报告有最高的失败率。本文旨在评估用纳米氟化银(NSF)预处理在抑制牙齿修复界面继发龋方面的有效性。

材料与方法

从20颗新拔除的人类前磨牙中通过近远中向切片制备40颗牙齿标本。在每个标本的釉质牙本质交界处制备V类洞。标本随机分为四组(n = 10):1)玻璃离子水门汀(GIC)修复,2)复合树脂修复,3)NSF预处理+GIC修复,4)NSF预处理+复合树脂修复。灭菌后,通过pH循环法对标本进行人工龋形成14天。将标本切片并安装以使用维氏显微硬度测试评估脱矿情况。在数字X线片上测量牙齿修复界面处的外层病变深度。使用学生非配对t检验、单因素方差分析和Tukey真实显著差异(HSD)事后检验分析数据。

结果

用NSF预处理过的GIC组和复合树脂组的平均显微硬度值高于未处理的NSF组,在釉质处有显著差异,表明脱矿较少。预处理组的外层病变深度较小,显示出更好的牙齿修复完整性,各组之间有统计学显著差异。

结论

用NSF预处理有利于提高GIC和复合树脂修复体对继发龋形成的抵抗力。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/062e/7265756/379f1b06b0dd/cureus-0012-00000007934-i01.jpg

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